Sui L, Xie F, Cao B
Obstetrics and Gynecology Hospital, Diagnostic & Treatment Center for Cervical Disease, Fudan University, 419 Fang-xie Road, Shanghai 200011, China.
Int J Gynecol Cancer. 2006 May-Jun;16(3):1482-6. doi: 10.1111/j.1525-1438.2006.00558.x.
The aim of the study was to assess the feasibility and effect of treating atypical endometrial hyperplasia (AEH) with transcervical resection of endometrium (TCRE). Five cases of AEH incapable of hysterectomy for various reasons were treated with TCRE. All patients were followed up for 3-4 years postoperation to evaluate the thickness of endometrium, uterine cavity, and prognosis of the disease. All the patients provided informed consent for TCRE. In all five cases treated with TCRE, case 1 was for senility, hypertension, diabetes mellitus, and obesity; case 4 for senility, obsolete cerebral infarction, and hemiplegia; case 5 for uremia and chronic dysfunction of coagulation after renal transplantation; cases 2 and 3 for rejection of hysterectomy. All cases were followed up for more than 3 years after operation. Four had amenorrhea and one had dropping menses. The thickness of endometrium was no more than 5 mm in all the cases. TCRE is one available microinvasive surgery alternative to hysterectomy for AEH patients contraindicated to hysterectomy.
本研究的目的是评估经宫颈子宫内膜切除术（TCRE）治疗非典型子宫内膜增生（AEH）的可行性和效果。对5例因各种原因无法进行子宫切除术的AEH患者进行了TCRE治疗。所有患者术后随访3 - 4年，以评估子宫内膜厚度、子宫腔情况及疾病预后。所有患者均对TCRE给予了知情同意。在接受TCRE治疗的5例患者中，病例1为老年、高血压、糖尿病和肥胖患者；病例4为老年、陈旧性脑梗死和偏瘫患者；病例5为尿毒症及肾移植后慢性凝血功能障碍患者；病例2和3为拒绝子宫切除术患者。所有病例术后随访均超过3年。4例闭经，1例月经减少。所有病例子宫内膜厚度均不超过5mm。对于禁忌子宫切除术的AEH患者，TCRE是一种可行的替代子宫切除术的微创手术方法。
