Fischbach M, Mengus L, Birmele B, Hamel G, Simeoni U, Geisert J
Nephrology-Dialysis-Transplantation-Children Unit, Hôpital Hautepierre, Strasbourg, France.
Adv Perit Dial. 1991;7:262-5.
Glucose is absorbed from the dialysate more rapidly in younger than in older children on CAPD leading to a relatively early loss of ultrafiltration during dwell time. In order to assess peritoneal permeability and in term to prescribe optimal management of CAPD, we tested peritoneal equilibration curves (EC) for urea and glucose, especially the crossing time point of these two ECs. Baseline values were obtained from 8 patients divided in two groups by age at start of CAPD: group I (N = 4) mean age 1 year 6 months, mean body weight 8.25 +/- 3.17 kg, group II (N = 4) mean age 12 years 6 months, mean body weight 33.5 +/- 1.5 kg. The crossing time point is earlier in group I (49 +/- 14 min) than in group II (101 +/- 20 min) (p less than 0.001). Followup of each patient, during a mean time of 20 months in group I and 23 months in group II, establishes that the curves crossing time point for each patient remains stable.
在持续性非卧床腹膜透析（CAPD）中，葡萄糖从透析液中的吸收在年幼儿童比年长儿童更快，导致在驻留时间内超滤相对较早丧失。为了评估腹膜通透性并从而制定CAPD的最佳管理方案，我们测试了尿素和葡萄糖的腹膜平衡曲线（EC），尤其是这两条EC的交叉时间点。基线值取自8例在开始CAPD时按年龄分为两组的患者：第一组（N = 4）平均年龄1岁6个月，平均体重8.25 +/- 3.17千克，第二组（N = 4）平均年龄12岁6个月，平均体重33.5 +/- 1.5千克。第一组的交叉时间点（49 +/- 14分钟）比第二组（101 +/- 20分钟）更早（p小于0.001）。对每位患者进行随访，第一组平均随访20个月，第二组平均随访23个月，结果表明每位患者的曲线交叉时间点保持稳定。
