Muris Joris, Feilzer Albert J
Department of Dental Materials Science, ACTA, Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, the Netherlands.
Neuro Endocrinol Lett. 2006 Dec;27 Suppl 1:49-52.
In dentistry, a variety of potentially allergenic metals are used, such as mercury, palladium, nickel, gold, chromium, cobalt and other metals. This paper describes a diagnostic approach from a dentist's point of view, which enables analysis of metals in a patient's oral cavity. If metal allergy is suspected, a micro analysis can be used to determine which metals are present in the restorations. When the exact composition of the dental materials is known, the patient can be tested in vivo (patch test) and/or in vitro (lymphocyte proliferation test) to reveal sensitization. Two patients with nickel allergy are described where removal of nickel-containing materials (bridge and orthodontic wire) resulted in the marked alleviation of symptoms and improvement of health. Finally, if allergy to specific metals has been established, the restorations containing the implicated metals should be removed to discontinue the exposure and thus facilitate the patient's health.
在牙科领域,使用了多种具有潜在致敏性的金属,如汞、钯、镍、金、铬、钴及其他金属。本文从牙医的角度描述了一种诊断方法,该方法能够分析患者口腔中的金属。如果怀疑存在金属过敏,可以使用微量分析来确定修复体中存在哪些金属。当牙科材料的确切成分已知时,可以对患者进行体内(斑贴试验)和/或体外(淋巴细胞增殖试验)检测,以揭示致敏情况。文中描述了两名镍过敏患者,去除含镍材料(牙桥和正畸钢丝)后症状明显缓解,健康状况得到改善。最后,如果已确定对特定金属过敏,应去除含有相关金属的修复体,以停止接触,从而促进患者健康。