Klont Rocus R, Mennink-Kersten Monique A S H, Ruegebrink Dorien, Rijs Antonius J M M, Blijlevens Nicole M A, Donnelly J Peter, Verweij Paul E
Department of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
Clin Infect Dis. 2006 Aug 1;43(3):e23-5. doi: 10.1086/505603. Epub 2006 Jun 19.
A paradoxical increase in circulating Aspergillus antigen was observed during treatment with caspofungin in a patient with proven invasive aspergillosis. With the exception of treatment with the echinocandin, no other factors were found that might explain this clinical observation, which was supported by experiments done in vitro.
在一名确诊为侵袭性曲霉病的患者接受卡泊芬净治疗期间，观察到循环曲霉抗原出现矛盾性增加。除了使用棘白菌素进行治疗外，未发现其他可能解释这一临床观察结果的因素，体外实验也支持了这一结果。
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