Mironov Vladimir, Visconti Richard P, Markwald Roger R
Medical University of South Carolina, Department of Cell Biology and Anatomy, PO Box 250508, Charleston, SC 29425, USA.
Expert Opin Biol Ther. 2006 Jul;6(7):727-30. doi: 10.1517/14712598.6.7.727.
Several years ago, the American Association of Anatomists (AAA) launched an innovative mini-meeting format as part of their annual meeting. The AAA continued this tradition by sponsoring a 2-day mini-symposium as a part of its meeting at FASEB Experimental Biology, 2006 in San Francisco, CA, USA. This year, the mini-symposium was focused on the promising and rapidly developing field of 'regenerative medicine'. The mini-symposium on 'regenerative medicine' included four separate but thematically integrated sessions: stem cells for regenerative medicine; biomimetic matrices for regenerative medicine; endothelial-mesenchymal transformation in cardiovascular regenerative medicine; and tissue engineering technologies for regenerative medicine. The goal of these sessions was to identify progress and highlight new trends and directions in the evolving field of regenerative medicine. It was an exciting 2-day mini-symposium that reviewed the differential potential of embryonic and adult stem cells, their role in tissue turnover and possible applications in tissue regeneration; identified important evolving basic science issues, such as the role of endothelial-mesenchymal transformation and stem cell recruitment in cardiovascular regenerative medicine; and, finally, clearly demonstrated how understanding basic scientific principles can be translated into novel cell therapeutics and tissue engineering modalities. The workshop also demonstrated the multidisciplinary (speakers included stem cell and developmental biologists, chemical engineers, tissue engineers, biophysicists, mathematicians and surgeons) and international (speakers represented US, Japan, Canada, Switzerland and Korea) character of ongoing efforts in the area of regenerative medicine and stem cell biology, impressive progress in this field, and confirmed the strong potential for clinical translation of emerging regenerative medicine technologies.
几年前,美国解剖学家协会(AAA)推出了一种创新的小型会议形式作为其年会的一部分。AAA延续了这一传统,于2006年在美国加利福尼亚州旧金山举办的FASEB实验生物学会议期间,赞助了一场为期两天的小型研讨会。今年,该小型研讨会聚焦于前景广阔且发展迅速的“再生医学”领域。关于“再生医学”的小型研讨会包括四个独立但主题相关的会议:用于再生医学的干细胞;用于再生医学的仿生基质;心血管再生医学中的内皮-间充质转化;以及用于再生医学的组织工程技术。这些会议的目标是确定进展,并突出再生医学这一不断发展领域中的新趋势和新方向。这是一场令人兴奋的为期两天的小型研讨会,它回顾了胚胎干细胞和成体干细胞的不同潜能、它们在组织更新中的作用以及在组织再生中的可能应用;确定了重要的正在演变的基础科学问题,比如内皮-间充质转化和干细胞募集在心血管再生医学中的作用;最后,清楚地展示了如何将对基础科学原理的理解转化为新型细胞治疗方法和组织工程模式。该研讨会还展示了再生医学和干细胞生物学领域当前工作的多学科性质(发言者包括干细胞和发育生物学家、化学工程师、组织工程师、生物物理学家、数学家和外科医生)以及国际性(发言者代表美国、日本、加拿大、瑞士和韩国),该领域取得的令人印象深刻的进展,并证实了新兴再生医学技术临床转化的强大潜力。