Tan Xiao-yan, He Jian-guo, Zou Zhi-peng, Zhao Yan-fen, Chen Bai-ping, Gao Ying, Xiong Chang-ming, Ni Xin-hai, Cheng Xian-sheng
Centre of Diagnosis and Management of Pulmonary Vascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.
Chin Med J (Engl). 2006 Jun 20;119(12):998-1002.
Pulmonary thromboembolism (PTE) has become a common disease that severely endangers people's health. This study analysed the changes in proportion and mortality of PTE in hospitalized patients to provide data for prevention and management of the disease.
The data of 763 hospitalized patients with PTE from 1974 to 2005 in Fuwai Hospital were analysed.
During the 1970s, 0.27% of patients in a cardiovascular hospital had PTE (< 5 cases per year); while so far this century the proportion is 0.94% (48 to 113 per year). The mortality of hospitalized PTE patients fell from 20.00% in the 1970s to 4.10% this century. Prior to 1990, the mortality of hospitalized PTE patients was 12.50%, and in the years after 1990 only 3.40%. The difference was statistically significant (P < 0.005). People with this disease were mostly between the ages of 30 and 69 years. Men were most susceptible between the ages of 30 and 69 years, while women between the ages of 40 and 69 years. Men contracted PTE 10 years earlier than women. The mortality of male PTE patients was 4.70%, not significantly different from female patients, 5.06% (0.50 < P < 0.75). There were not any significant differences between the mortality of patients in the different age groups overall (< or = 39, 40 - 49, 50 - 59, and > or = 60 years, P > 0.1). More people contracted the disease in winter than in other seasons (P < 0.05). There was no obvious difference between the mortality in different seasons overall (0.75 < P < 0.90).
PTE is an increasingly significant disease and deserves adequate attention.
肺血栓栓塞症（PTE）已成为严重危害人们健康的常见疾病。本研究分析住院患者中PTE的比例及死亡率变化，为该病的预防和管理提供数据。
分析了1974年至2005年阜外医院763例住院PTE患者的数据。
20世纪70年代，心血管病医院中0.27%的患者患有PTE（每年<5例）；而到本世纪至今，这一比例为0.94%（每年48至113例）。住院PTE患者的死亡率从20世纪70年代的20.00%降至本世纪的4.10%。1990年前，住院PTE患者的死亡率为12.50%，1990年后仅为3.40%。差异有统计学意义（P<0.005）。该病患者多为30至69岁。男性在30至69岁时最易患病，女性在40至69岁时最易患病。男性患PTE比女性早10年。男性PTE患者的死亡率为4.70%，与女性患者的5.06%无显著差异（0.50<P<0.75）。不同年龄组患者的总体死亡率之间无显著差异（≤39岁、40 - 49岁、50 - 59岁和≥60岁，P>0.1）。冬季患病的人比其他季节多（P<0.05）。不同季节的总体死亡率之间无明显差异（0.75<P<0.90）。
PTE是一种日益重要的疾病，值得给予充分关注。
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