骨骼肌损伤后间充质细胞向血液中的动员。
Mobilisation of mesenchymal cells into blood in response to skeletal muscle injury.
作者信息
Ramírez M, Lucia A, Gómez-Gallego F, Esteve-Lanao J, Pérez-Martínez A, Foster C, Andreu A L, Martin M A, Madero L, Arenas J, García-Castro J
机构信息
Servicio de Oncohematología y Transplante, Hospital Universitario Niño Jesús, Avda Menéndez Pelayo 65, 28009 Madrid, Spain.
出版信息
Br J Sports Med. 2006 Aug;40(8):719-22. doi: 10.1136/bjsm.2006.028639. Epub 2006 Jun 28.
Abstract
Mesenchymal cells recruited to damaged tissues must circulate through the bloodstream. The absolute numbers of circulating mesenchymal stem cells (cMSCs) in two different models of acute and chronic skeletal muscle injury were determined. cMSCs were present in significantly higher numbers in both models than in healthy controls. These results support the hypothesis that MSCs are mobilised into the bloodstream after skeletal muscle tissue damage. These two models (acute and chronic) would be of value in the search for molecular mediators of mobilisation of MSCs into the circulation.
摘要
招募至受损组织的间充质细胞必须通过血液循环。测定了急性和慢性骨骼肌损伤两种不同模型中循环间充质干细胞（cMSC）的绝对数量。在这两种模型中，cMSC的数量均显著高于健康对照。这些结果支持了骨骼肌组织损伤后间充质干细胞被动员进入血液循环的假说。这两种模型（急性和慢性）对于寻找间充质干细胞动员进入循环的分子介质具有重要价值。
相似文献
1
Mobilisation of mesenchymal cells into blood in response to skeletal muscle injury.骨骼肌损伤后间充质细胞向血液中的动员。
Br J Sports Med. 2006 Aug;40(8):719-22. doi: 10.1136/bjsm.2006.028639. Epub 2006 Jun 28.
2
McArdle disease: another systemic low-inflammation disorder?麦卡德尔病：另一种全身性低炎症性疾病？
Neurosci Lett. 2008 Jan 31;431(2):106-11. doi: 10.1016/j.neulet.2007.11.028. Epub 2007 Dec 4.
3
Release of alpha-actin into serum after skeletal muscle damage.骨骼肌损伤后α-肌动蛋白释放至血清中。
Br J Sports Med. 2005 Nov;39(11):830-4. doi: 10.1136/bjsm.2004.017566.
4
Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.用于组织工程与再生医学的成人间充质干细胞。
J Cell Physiol. 2007 Nov;213(2):341-7. doi: 10.1002/jcp.21200.
5
Mobilisation of mesenchymal cells in cardiac patients: is intense exercise necessary?心脏病患者间充质细胞的动员：高强度运动是否必要？
Br J Sports Med. 2009 Mar;43(3):221-3. doi: 10.1136/bjsm.2007.044693. Epub 2008 Apr 9.
6
Is the intravascular administration of mesenchymal stem cells safe? Mesenchymal stem cells and intravital microscopy.间充质干细胞的血管内给药安全吗？间充质干细胞与活体显微镜检查。
Microvasc Res. 2009 May;77(3):370-6. doi: 10.1016/j.mvr.2009.02.001. Epub 2009 Feb 26.
7
Allogeneic mesenchymal stem cell and mesenchymal stem cell-differentiated chondrocyte suppress the responses of type II collagen-reactive T cells in rheumatoid arthritis.同种异体间充质干细胞和间充质干细胞分化的软骨细胞可抑制类风湿关节炎中II型胶原反应性T细胞的反应。
Rheumatology (Oxford). 2008 Jan;47(1):22-30. doi: 10.1093/rheumatology/kem284.
8
Impairment of endothelial cell differentiation from bone marrow-derived mesenchymal stem cells: new insight into the pathogenesis of systemic sclerosis.骨髓间充质干细胞向内皮细胞分化的受损：系统性硬化症发病机制的新见解。
Arthritis Rheum. 2007 Jun;56(6):1994-2004. doi: 10.1002/art.22698.
9
Validity of serum creatine kinase as a measure of muscle injury produced by lumbar surgery.血清肌酸激酶作为腰椎手术所致肌肉损伤指标的有效性。
J Spinal Disord Tech. 2008 Feb;21(1):49-54. doi: 10.1097/BSD.0b013e31805777fb.
10
Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells.食蟹猴间充质干细胞的分离、鉴定及基因修饰
Differentiation. 2009 Mar;77(3):256-62. doi: 10.1016/j.diff.2008.09.021. Epub 2008 Dec 2.
引用本文的文献
1
Exploring mesenchymal stem cells homing mechanisms and improvement strategies.探索间充质干细胞归巢机制及改善策略。
Stem Cells Transl Med. 2024 Dec 16;13(12):1161-1177. doi: 10.1093/stcltm/szae045.
2
Acute Exercise-Induced Oxidative Stress Does Not Affect Immediate or Delayed Precursor Cell Mobilization in Healthy Young Males.急性运动诱导的氧化应激对健康年轻男性即刻或延迟前体细胞动员无影响。
Front Physiol. 2020 Oct 20;11:577540. doi: 10.3389/fphys.2020.577540. eCollection 2020.
3
Influence of reaming intramedullary nailing on MSC population after surgical treatment of patients with long bone fracture.扩髓髓内钉固定对长骨骨折患者手术后间充质干细胞群体的影响。
Mol Med Rep. 2020 Sep;22(3):2521-2527. doi: 10.3892/mmr.2020.11320. Epub 2020 Jul 9.
4
Canagliflozin impairs blood reperfusion of ischaemic lower limb partially by inhibiting the retention and paracrine function of bone marrow derived mesenchymal stem cells.卡格列净部分通过抑制骨髓间充质干细胞的滞留和旁分泌功能来损害缺血性下肢的血液再灌注。
EBioMedicine. 2020 Feb;52:102637. doi: 10.1016/j.ebiom.2020.102637. Epub 2020 Jan 22.
5
αCGRP Affects BMSCs' Migration and Osteogenesis via the Hippo-YAP Pathway.αCGRP 通过 Hippo-YAP 通路影响 BMSCs 的迁移和成骨作用。
Cell Transplant. 2019 Nov;28(11):1420-1431. doi: 10.1177/0963689719871000. Epub 2019 Aug 19.
6
Mesenchymal stem cells in peripheral blood of severely injured patients.重伤患者外周血中的间充质干细胞。
Eur J Trauma Emerg Surg. 2018 Aug;44(4):627-636. doi: 10.1007/s00068-017-0849-8. Epub 2017 Oct 6.
7
Trauma and Stem Cells: Biology and Potential Therapeutic Implications.创伤与干细胞：生物学及潜在治疗意义
Int J Mol Sci. 2017 Mar 7;18(3):577. doi: 10.3390/ijms18030577.
8
Mesenchymal Stem Cells after Polytrauma: Actor and Target.多发伤后的间充质干细胞：作用者与靶点
Stem Cells Int. 2016;2016:6289825. doi: 10.1155/2016/6289825. Epub 2016 Jun 2.
9
Mesenchymal stem cells: A new diagnostic tool?间充质干细胞：一种新的诊断工具？
World J Stem Cells. 2015 Jun 26;7(5):789-92. doi: 10.4252/wjsc.v7.i5.789.
10
Optimization of pre-transplantation conditions to enhance the efficacy of mesenchymal stem cells.优化移植前条件以提高间充质干细胞的疗效。
Int J Biol Sci. 2015 Feb 5;11(3):324-34. doi: 10.7150/ijbs.10567. eCollection 2015.
本文引用的文献
1
Myopathy due to a defect in muscle glycogen breakdown.由于肌肉糖原分解缺陷导致的肌病。
Clin Sci. 1951 Feb;10(1):13-35.
2
Muscle stem cells and regenerative myogenesis.肌肉干细胞与再生性肌生成
Curr Top Dev Biol. 2005;71:113-30. doi: 10.1016/S0070-2153(05)71004-8.
3
Responses of N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac troponin I (cTnI) to competitive endurance exercise in recreational athletes.N端前脑钠肽（NT-proBNP）和心肌肌钙蛋白I（cTnI）对业余运动员竞争性耐力运动的反应。
Int J Sports Med. 2005 Oct;26(8):645-50. doi: 10.1055/s-2004-830491.
4
Mesenchymal stem cells: progress toward promise.间充质干细胞：迈向希望的进展。
Cytotherapy. 2005;7(1):36-45. doi: 10.1080/14653240510018118.
5
Exercise-induced muscle damage, plasma cytokines, and markers of neutrophil activation.运动诱导的肌肉损伤、血浆细胞因子及中性粒细胞活化标志物。
Med Sci Sports Exerc. 2005 May;37(5):737-45. doi: 10.1249/01.mss.0000161804.05399.3b.
6
Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue.人骨髓和脂肪组织间充质干细胞的鉴定与表达分析
Cell Physiol Biochem. 2004;14(4-6):311-24. doi: 10.1159/000080341.
7
Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma.骨髓基质来源的成人干细胞在体外修复上皮过程中的分化、细胞融合和核融合。
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2397-402. doi: 10.1073/pnas.0437997100. Epub 2003 Feb 26.
8
Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors.骨髓间充质干细胞作为将β-干扰素递送至肿瘤的载体。
Cancer Res. 2002 Jul 1;62(13):3603-8.
9
Intracerebral transplantation of mesenchymal stem cells into acid sphingomyelinase-deficient mice delays the onset of neurological abnormalities and extends their life span.将间充质干细胞脑内移植到酸性鞘磷脂酶缺陷小鼠中可延迟神经异常的发作并延长其寿命。
J Clin Invest. 2002 May;109(9):1183-91. doi: 10.1172/JCI14862.
Zotero 插件