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先天性异常肾脏结石的治疗:体外冲击波碎石术疗效评估

Treatment of calculi in kidneys with congenital anomalies: an assessment of the efficacy of lithotripsy.

作者信息

Al-Tawheed Adel R, Al-Awadi Khaleel A, Kehinde Elijah O, Abdul-Halim Hamdy, Hanafi Akram M, Ali Yusuf

机构信息

Department of Surgery (Division of Urology), Mubarak Al-Kabeer Hospital, Safat, Kuwait.

出版信息

Urol Res. 2006 Oct;34(5):291-8. doi: 10.1007/s00240-006-0059-z. Epub 2006 Jun 29.

Abstract

We studied the effectiveness of extracorporeal shock wave lithotripsy (ESWL) in the treatment of stones in kidneys with congenital anomalies to determine factors that may affect the results. Patients found to have renal calculi in kidneys with different types of congenital anomalies were treated using ESWL. All patients were investigated by intravenous urography (IVU) to confirm the diagnosis. J stents were inserted prior to therapy in renal units with calculi exceeding 1.5 cm in diameter. Complications encountered and factors affecting success using this treatment modality were analysed. Twenty-five patients (18 males, 7 females) were studied between August 1988 and July 2005. There were nine patients with horseshoe kidneys, eight with ectopic kidneys, three with malrotated kidneys, two with duplex renal system, and one patient each with polycystic kidneys and hypoplastic kidney. The IVU showed 31 isolated calyceal or renal pelvic stones with mean stone burden of 1.44cc. All 25 patients were treated by lithotripsy. Twenty-four (77.4%) renal units (in 19 patients) were completely cleared of stones, 2 (6.5%) renal units (2 patients) were partially cleared of calculi and the procedures failed in 5 (16.1%) renal units (4 patients). Out of five renal units in which the procedures failed, open surgery was performed in three renal units and percutaneous nephrolithotomy (PCNL) was performed in two. None of the 25 patients developed any major complications. No significant adverse changes in renal function tests were observed at 3-month follow-up. The stone-free rate was influenced and reduced by stone size and location in the pelvi-calyceal system. Calculi in kidneys with congenital anomalies may be treated successfully by ESWL as a first-line therapy in the majority of patients. With position modifications, localization of stones may be facilitated and disintegrated. The outcome in patients so treated does not differ significantly from that in those with normal kidneys.

摘要

我们研究了体外冲击波碎石术(ESWL)治疗先天性异常肾脏结石的有效性,以确定可能影响治疗结果的因素。对发现患有不同类型先天性异常肾脏结石的患者采用ESWL进行治疗。所有患者均接受静脉肾盂造影(IVU)检查以确诊。对于直径超过1.5 cm结石的肾单位,在治疗前插入J形支架。分析了使用这种治疗方式时遇到的并发症以及影响治疗成功的因素。1988年8月至2005年7月期间对25例患者(18例男性,7例女性)进行了研究。其中马蹄肾9例,异位肾8例,旋转不良肾3例,重复肾系统2例,多囊肾和发育不全肾各1例。IVU显示31枚孤立的肾盏或肾盂结石,平均结石体积为1.44cc。所有25例患者均接受了碎石治疗。24个(77.4%)肾单位(19例患者)结石完全清除,2个(6.5%)肾单位(2例患者)结石部分清除,5个(16.1%)肾单位(4例患者)治疗失败。在治疗失败的5个肾单位中,3个肾单位进行了开放手术,2个肾单位进行了经皮肾镜取石术(PCNL)。25例患者均未发生任何严重并发症。在3个月的随访中,未观察到肾功能检查有明显的不良变化。结石清除率受肾盂肾盏系统中结石大小和位置的影响而降低。先天性异常肾脏的结石在大多数患者中可作为一线治疗通过ESWL成功治疗。通过调整体位,可便于结石定位并将其击碎。接受此类治疗的患者的治疗结果与正常肾脏患者的结果无显著差异。

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