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聚维酮碘硬化疗法治疗有症状的肾囊肿无效。

Povidone-iodine sclerotherapy is ineffective in the treatment of symptomatic renal cysts.

作者信息

Madeb Ralph, Feldman Paul A, Knopf Joy, Rub Ronen, Erturk Erdal, Yachia Daniel

机构信息

Department of Urology, University of Rochester School of Medicine, Rochester, New York, USA.

出版信息

J Endourol. 2006 Jun;20(6):402-4. doi: 10.1089/end.2006.20.402.

Abstract

PURPOSE

To evaluate the efficacy of povidone-iodine sclerotherapy after percutaneous drainage of simple renal cysts in the treatment of symptomatic patients.

PATIENTS AND METHODS

Sixteen patients with symptomatic renal cysts were treated by percutaneous drainage and injection of povidone-iodine solution. The cysts were drained by a nephrostomy tube catheter, and povidone- iodine injections were repeated every 24 hours for 3 days. All patients were followed up by ultrasound examination during a period ranging from 1 to 4 years (mean 1.8 years).

RESULTS

Thirteen patients experienced recurrence of cysts, while complete resolution was observed in only three patients. Of the cysts that recurred, only partial resolution in cyst diameter was observed (from 3-10.5 cm to 2.4-8.6 cm). During the follow-up period, 12 of the 16 patients (75%) continued to have pain that necessitated additional treatments.

CONCLUSION

Povidone-iodine sclerotherapy is followed by a high rate of recurrence and is therefore not indicated for the treatment of symptomatic simple renal cysts.

摘要

目的

评估单纯性肾囊肿经皮引流后聚维酮碘硬化疗法对有症状患者的治疗效果。

患者与方法

16例有症状的肾囊肿患者接受了经皮引流及聚维酮碘溶液注射治疗。通过肾造瘘管导管引流囊肿,并每24小时重复注射聚维酮碘,持续3天。所有患者在1至4年(平均1.8年)的时间里接受超声检查随访。

结果

13例患者囊肿复发,仅3例患者囊肿完全消退。在复发的囊肿中,仅观察到囊肿直径部分缩小(从3 - 10.5厘米缩小至2.4 - 8.6厘米)。在随访期间,16例患者中有12例(75%)持续存在疼痛,需要进一步治疗。

结论

聚维酮碘硬化疗法后复发率高,因此不适合用于治疗有症状的单纯性肾囊肿。

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