Serter Selim, Gümüş Bilal, Unlü Murat, Tunçyürek Ozüm, Tarhan Serdar, Ayyildiz Veli, Pabuscu Yüksel
Departments of Radiology, School of Medicine, Celal Bayar University, Manisa, Turkey.
Scand J Urol Nephrol. 2006;40(3):212-4. doi: 10.1080/00365590600589641.
Testicular microlithiasis is a rare, usually asymptomatic, finding of the testes associated with various genetic anomalies and infertility. It is also widely believed that testicular microlithiasis is strongly associated with testicular tumor. The aim of this prospective study was to determine the true prevalence of testicular microlithiasis in an asymptomatic population by means of ultrasound screening.
Healthy male volunteers (17-42 years old) were recruited from the annual Army Reserve Officer Training Corps training camp at Manisa, Turkey. A screening genitourinary history was obtained and a physical examination and screening scrotal ultrasound scan were performed.
All men diagnosed with testicular microlithiasis underwent complete clinical evaluations, physical examinations and determination of tumor markers. Fifty-three men with testicular microlithiasis were identified from the 2179 ultrasound scans, giving a prevalence of testicular microlithiasis of 2.4% in this asymptomatic population. The age (mean+/-SD) of subjects with testicular microlithiasis was 23.9+/-4.2 years (range 20-31 years).
Our results suggest that there is no significant association between TM and testicular cancer, although it is difficult to rule out such an association without further studies with a longer follow-up period.
睾丸微石症是一种罕见的、通常无症状的睾丸表现，与各种基因异常及不育相关。人们还普遍认为睾丸微石症与睾丸肿瘤密切相关。这项前瞻性研究的目的是通过超声筛查确定无症状人群中睾丸微石症的真实患病率。
从土耳其马尼萨的年度陆军后备军官训练团训练营招募健康男性志愿者（17 - 42岁）。获取泌尿生殖系统筛查病史，并进行体格检查和阴囊超声筛查。
所有诊断为睾丸微石症的男性均接受了全面的临床评估、体格检查及肿瘤标志物检测。在2179次超声检查中，发现53例睾丸微石症患者，该无症状人群中睾丸微石症的患病率为2.4%。睾丸微石症患者的年龄（均值±标准差）为23.9±4.2岁（范围20 - 31岁）。
我们的结果表明，睾丸微石症与睾丸癌之间无显著关联，尽管在没有更长随访期的进一步研究情况下难以排除这种关联。
