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FGF-2 protects small cell lung cancer cells from apoptosis through a complex involving PKCepsilon, B-Raf and S6K2.
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Novel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cells.
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Non-receptor tyrosine kinase Etk is involved in the apoptosis of small cell lung cancer cells.
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Non-receptor tyrosine kinase Etk regulation of drug resistance in small-cell lung cancer.
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Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells.
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PKC controls HGF-dependent c-Met traffic, signalling and cell migration.
EMBO J. 2004 Oct 1;23(19):3721-34. doi: 10.1038/sj.emboj.7600396. Epub 2004 Sep 23.
3
SKAR is a specific target of S6 kinase 1 in cell growth control.
Curr Biol. 2004 Sep 7;14(17):1540-9. doi: 10.1016/j.cub.2004.08.061.
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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.
Cell. 2004 Mar 19;116(6):855-67. doi: 10.1016/s0092-8674(04)00215-6.
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Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway.
J Biol Chem. 2003 Oct 24;278(43):42409-18. doi: 10.1074/jbc.M308709200. Epub 2003 Aug 12.
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