印度北部大规模疫情期间肝炎患者粪便中的戊型肝炎病毒基因组

Hepatitis E virus genome in stools of hepatitis patients during large epidemic in north India.

作者信息

Ray R, Aggarwal R, Salunke P N, Mehrotra N N, Talwar G P, Naik S R

机构信息

National Institute of Immunology, New Delhi, India.

出版信息

Lancet. 1991 Sep 28;338(8770):783-4. doi: 10.1016/0140-6736(91)90667-e.

DOI:10.1016/0140-6736(91)90667-e

PMID:1681163

Abstract

Stool samples from patients affected during a large epidemic of hepatitis in north India were examined for the presence of hepatitis E virus (HEV) genome by means of reverse transcription-polymerase chain reaction. 6 of 10 samples studied were positive for the HEV genome, which suggest that HEV caused this large epidemic.

摘要

通过逆转录聚合酶链反应，对印度北部一次大规模肝炎流行期间受感染患者的粪便样本进行了检查，以确定是否存在戊型肝炎病毒（HEV）基因组。在研究的10个样本中，有6个样本的HEV基因组呈阳性，这表明HEV导致了这次大规模流行。