藏红花（番红花）柱头和花瓣及其成分藏红花醛和藏红花素对豚鼠镇咳作用的评价。
Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs.
作者信息
Hosseinzadeh Hossein, Ghenaati Jafar
机构信息
Pharmacology and Toxicology Department, Pharmaceutical Research Center, Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IR, Iran.
出版信息
Fitoterapia. 2006 Sep;77(6):446-8. doi: 10.1016/j.fitote.2006.04.012. Epub 2006 May 24.
The antitussive activity of Crocus sativus stigma and petal extracts and its components, safranal and crocin, was evaluated using the nebolized solution of citric acid 20% in guinea pigs. The extract and agents were injected intraperitoneally. The ethanolic extract of C. sativus (100-800 mg/kg) and safranal (0.25-0.75 ml/kg) reduced the number of cough. The ethanolic and aqueous extracts of petal and crocin did not show antitussive activity.
采用20%柠檬酸雾化溶液对豚鼠进行实验，评估了藏红花柱头和花瓣提取物及其成分藏红花醛和藏红花素的镇咳活性。提取物和制剂通过腹腔注射给药。藏红花乙醇提取物（100 - 800毫克/千克）和藏红花醛（0.25 - 0.75毫升/千克）可减少咳嗽次数。花瓣的乙醇提取物和水提取物以及藏红花素未显示出镇咳活性。
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