新生儿重症监护队列中的眼部耐甲氧西林金黄色葡萄球菌感染
Ocular methicillin-resistant Staphylococcus aureus infections in a newborn intensive care cohort.
作者信息
Cimolai Nevio
机构信息
Program of Microbiology, Virology, and Infection Control, Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia, Vancouver, British Columbia, Canada.
出版信息
Am J Ophthalmol. 2006 Jul;142(1):183-4. doi: 10.1016/j.ajo.2006.02.019.
PURPOSE
To examine the occurrence and outcome of methicillin-resistant Staphylococcus aureus ophthalmologic infections in a newborn intensive care unit cohort.
DESIGN
Noninterventional case series.
METHODS
Over a 13-month period, 29 neonates were colonized with methicillin-resistant S. aureus in a newborn intensive care unit outbreak. Patients were followed prospectively during the course of colonization and infection. The frequency and type of ophthalmologic infection was recorded, and patients were treated according to clinical need.
RESULTS
Eleven of these patients were found to have purulent conjunctivitis. No serious ocular disease ensued in any of these. Spontaneous resolution occurred in some patients, while others improved after either topical or systemic antibiotic treatment.
CONCLUSION
Despite invasive infection caused by methicillin-resistant S. aureus, serious ophthalmologic infection was not found.
目的
研究新生儿重症监护病房队列中耐甲氧西林金黄色葡萄球菌眼部感染的发生情况及转归。
设计
非干预性病例系列研究。
方法
在13个月的时间里，29例新生儿在新生儿重症监护病房暴发感染时被耐甲氧西林金黄色葡萄球菌定植。在定植和感染过程中对患者进行前瞻性随访。记录眼部感染的频率和类型，并根据临床需要对患者进行治疗。
结果
这些患者中有11例被发现患有脓性结膜炎。这些患者均未出现严重眼部疾病。部分患者感染自行消退，而其他患者经局部或全身抗生素治疗后病情好转。
结论
尽管存在耐甲氧西林金黄色葡萄球菌引起的侵袭性感染，但未发现严重的眼部感染。
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