Poikkeus P, Saisto T, Unkila-Kallio L, Punamaki R-L, Repokari L, Vilska S, Tiitinen A, Tulppala M
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Finland.
Obstet Gynecol. 2006 Jul;108(1):70-6. doi: 10.1097/01.AOG.0000222902.37120.2f.
To compare the prevalence and predictors of severe fear of childbirth and pregnancy-related anxiety in groups of assisted reproduction treatment (ART) and spontaneously conceiving women with singleton pregnancies.
The ART group (n = 367, nulliparous 260) represented a cohort from five Finnish infertility clinics in 1999. The control group (n = 379, nulliparous 135) was enrolled in this study by consecutive sampling the same year. Fear of childbirth was assessed by means of the revised version of the Fear-of-Childbirth Questionnaire and pregnancy-related anxiety by means of the Pregnancy Anxiety Scale at gestational week 20 +/- 3.2 (mean+/-standard deviation).
The frequency of severe fear of childbirth and anxiety (classified as total scores in the 90th percentile or higher in the revised Fear of Childbirth Questionnaire and Pregnancy Anxiety Scale) did not differ between the groups. Nulliparity was associated with more frequent severe anxiety only in the controls. In nulliparous participants, a partnership of more than 5 years decreased the risk of severe fear of childbirth (odds ratio 0.3, 95% confidence interval 0.2-0.7). In the nulliparous ART group, a long duration of infertility (7 or more years) increased the risk of severe fear of childbirth (odds ratio 4.4, 95% confidence interval 1.2-16.9).
Women conceiving after ART do not experience severe fear of childbirth or pregnancy-related axiety more often than spontaneously conceiving controls. However, a long duration of infertility is an independent risk factor regarding severe fear of childbirth.
II-2.
比较接受辅助生殖治疗(ART)的单胎妊娠女性组和自然受孕女性组中严重分娩恐惧和妊娠相关焦虑的患病率及预测因素。
ART组(n = 367,未生育者260例)代表1999年来自芬兰五家不孕不育诊所的队列。对照组(n = 379,未生育者135例)于同年通过连续抽样纳入本研究。在妊娠第20±3.2周(均值±标准差),采用修订版分娩恐惧问卷评估分娩恐惧,采用妊娠焦虑量表评估妊娠相关焦虑。
两组间严重分娩恐惧和焦虑的发生率(在修订版分娩恐惧问卷和妊娠焦虑量表中分类为总分在第90百分位数或更高)无差异。仅在对照组中,未生育与更频繁的严重焦虑相关。在未生育参与者中,伴侣关系超过5年可降低严重分娩恐惧的风险(比值比0.3,95%置信区间0.2 - 0.7)。在未生育的ART组中,不孕持续时间长(7年或更长时间)会增加严重分娩恐惧的风险(比值比4.4,95%置信区间1.2 - 16.9)。
接受ART后受孕的女性并不比自然受孕的对照组更常经历严重分娩恐惧或妊娠相关焦虑。然而,不孕持续时间长是严重分娩恐惧的一个独立危险因素。
II - 2。