[The modulatory action of superlow doses of mediators on the functional activity of the neuronal membrane].

It was shown that acetylcholine and gamma-aminobutyric acid at extremely low concentrations, which do not activate receptor-binding ionic channels, modulate the activity of NA-K-pump and Na:Ca exchange, the intracellular level of cAMP and chemosensitivity of the neuronal membrane. These data provide a new evidence in support for Koshtoiants's enzymochemical hypothesis in which synaptic transmitters are considered to be metabolic modulators for postsynaptic neurones.