Hovi Minna, Raatikainen Kaisa, Heiskanen Nonna, Heinonen Seppo
Department of Gynaecology and Obstetrics, Kuopio University Hospital, Kuopio, Finland.
Acta Obstet Gynecol Scand. 2006;85(7):805-9. doi: 10.1080/00016340500442472.
The objective of this study was to determine the outcome of pregnancy in post-term cases compared with term cases in a well defined population receiving modern obstetric care.
We utilized the population-based birth registry data of the Kuopio University Hospital (1990-2000) to investigate pregnancy outcome in 1,678 post-term singleton pregnancies. The general obstetric population (n=22,712) was used as a reference group in logistic regression analysis.
The overall frequency of post-term pregnancies was 6.9% and the incidence of post-term pregnancies was found to be increased in obese, primiparous, and smoking women, whereas in women with chronic diseases and obstetric risks deliveries were induced earlier. The risks of macrosomia, maternal complications, and operative deliveries were increased in post-term pregnancies. Post-term infants experienced meconium passage (21.2% versus 12.8%) (p<0.01) and intrapartum asphyxia (3.4% versus 2.1%) (p<0.01) significantly more often than the controls. However, the stillbirth rate was low, probably due to careful monitoring of these pregnancies.
Although high-risk pregnancies were not allowed to come post-term, postmaturity per se is a moderate risk state compromising fetal well-being with regard to meconium passage and acid-base status at birth. We conclude that simple antenatal monitoring beyond 42 weeks reduces perinatal mortality but is inefficient in reducing meconium-stained liquor seen with increasing gestation.
本研究的目的是在接受现代产科护理的明确人群中,确定过期妊娠病例与足月妊娠病例的妊娠结局。
我们利用库奥皮奥大学医院基于人群的出生登记数据(1990 - 2000年),调查了1678例过期单胎妊娠的妊娠结局。在逻辑回归分析中,将一般产科人群(n = 22712)用作参照组。
过期妊娠的总体发生率为6.9%,发现肥胖、初产和吸烟女性的过期妊娠发生率增加,而患有慢性疾病和存在产科风险的女性分娩提前。过期妊娠中巨大儿、母亲并发症和手术分娩的风险增加。过期产儿胎粪排出(21.2%对12.8%)(p<0.01)和产时窒息(3.4%对2.1%)(p<0.01)的发生率明显高于对照组。然而,死产率较低,可能是由于对这些妊娠进行了仔细监测。
尽管不允许高危妊娠过期,但过期本身是一种中度风险状态,就出生时的胎粪排出和酸碱状态而言,会损害胎儿健康。我们得出结论,42周后简单的产前监测可降低围产期死亡率,但在减少随着孕周增加出现的羊水粪染方面效率不高。