Flati G, Porowska B, Flati D, Gaj F, Antonellis F, Nudo F, Berloco P B
Servizio Trapianti D'Organo, Dipartimento di Chirurgia "P. Stefanini", Università di Roma "La Sapienza", Roma, Italia.
Clin Ter. 2006 Mar-Apr;157(2):95-103.
To evaluate the quality of life after nerve sparing total mesorectal excision for rectal cancer.
Crucial technical aspects of the procedure such as the preservation of genitourinary innervation and the achievement of optimal local control of the disease have been emphasized. It is known that local recurrences, sexual and urinary dysfunctions may have a significant impact on postoperative quality of life of the patients. Postoperative evaluation of functional outcomes of nerve sparing total mesorectal excision has been carried out utilizing the QLQ C30 (version 3) (All CR38).
At one year follow-up 27.2% of the patients presented sexual activity related dysfunctions, 6.1% complained of urinary dysfunction and 21% of the patients complained of some significant psychologic disturbances.
A correct surgical dissection with preservation of inferior hypogastric plexus and all genitourinary nerve supply yield the best results either in terms of quality of life and of oncologic control of the disease.
评估保留神经的直肠癌全直肠系膜切除术后的生活质量。
强调了该手术的关键技术要点,如保留泌尿生殖神经支配以及实现疾病的最佳局部控制。众所周知,局部复发、性功能和排尿功能障碍可能对患者术后生活质量产生重大影响。利用QLQ C30(第3版)(所有CR38)对保留神经的全直肠系膜切除术后的功能结局进行了术后评估。
在1年随访时,27.2%的患者出现与性活动相关的功能障碍,6.1%的患者抱怨排尿功能障碍,21%的患者抱怨有一些明显的心理障碍。
正确的手术解剖并保留腹下神经丛和所有泌尿生殖神经供应,在生活质量和疾病的肿瘤学控制方面均能取得最佳效果。