Bai Hui, Li Li-Yun, Liu Guo-Zhen
College of Life Sciences, Hebei Agricultural University, Baoding, Hebei 071001, China.
Yi Chuan. 2006 Jun;28(6):745-53.
Gene Xa21 is the first disease resistance gene cloned from rice (Oryza sativa L.), which encodes a receptor-like kinase and confers broad spectrum resistance against Xanthomonas oryzae pv. oryzae (Xoo). In this paper, the discovery, mapping and cloning of Xa21 were reviewed briefly. The molecular mechanism of resistance and its breeding application, including biochemical properties of the kinase domain of XA21, AvrXa21 identification, the disease resistance pathway mediated by Xa21, and the mechanism of disease resistance were summarized. Future perspective on Xa21-related research is also discussed.
Xa21基因是从水稻(Oryza sativa L.)中克隆出的首个抗病基因,它编码一种类受体激酶,对水稻白叶枯病菌(Xanthomonas oryzae pv. oryzae,简称Xoo)具有广谱抗性。本文简要综述了Xa21基因的发现、定位和克隆过程。对抗性分子机制及其育种应用进行了总结,内容包括XA21激酶结构域的生化特性、AvrXa21的鉴定、Xa21介导的抗病途径以及抗病机制。同时也讨论了Xa21相关研究的未来展望。