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通过定量计算机断层扫描评估非骨水泥型全髋关节置换术后髋臼周围骨质变化。

Periacetabular bone changes after uncemented total hip arthroplasty evaluated by quantitative computed tomography.

作者信息

Mueller Lutz Arne, Kress Alexander, Nowak Tobias, Pfander David, Pitto Rocco Paolo, Forst Raimund, Schmidt Rainer

机构信息

Department of Orthopaedic Surgery, University of Erlangen-Nuremberg, Erlangen, Germany.

出版信息

Acta Orthop. 2006 Jun;77(3):380-5. doi: 10.1080/17453670610046299.

Abstract

BACKGROUND

There are few dual X-ray absorptiometry (DXA) studies on periacetabular bone density changes after cup implantation. This study was designed to analyze the load-transfer mechanism and stress pattern of periacetabular cortical and cancellous bone after implantation of a ihemispherical titanium alloy press-fit cup with alumina-alumina pairing in vivo. We introduced a novel method of computed tomography (CT)-assisted osteodensitometry.

METHOD

We investigated 26 hips (26 patients) with osteoarthritis using conventional sequential CT examinations performed within the first 10 days after implantation, and after a mean period of 1.1 years postoperatively. Bone density of full, cancellous and cortical bone (mgCaHA/mL) was measured.

RESULTS

At the time of follow-up, the mean bone density values of the cortical bone cranial to the cup increased by 3.6% (p = 0.03) while the cancellous bone density decreased by 18%. Cancellous bone loss was greater in the region ventral to the cup (-35%) than in the dorsal region (-30%). Cortical bone density decreased ventral to the cup (-6.4%). All these changes were statistically significant. The bone density changes in the dorsal cortical region were not significant.

INTERPRETATION

The method presented is an excellent tool for detailed measurement of bone density changes around the cup after total hip arthroplasty, and allows a thorough assessment of stress shielding phenomena in vivo. The hemispherical titanium alloy press-fit cup is a rigid implant which stress shields cancellous bone and enhances load transfer to the cranial cortical bone. Further investigations will demonstrate the impact these factors have on the long-term results of the implant, and may allow a type-related predictable prognosis of the longevity of the prosthesis.

摘要

背景

关于髋臼杯植入后髋臼周围骨密度变化的双能X线吸收法(DXA)研究较少。本研究旨在分析体内植入氧化铝-氧化铝配对的半球形钛合金压配式髋臼杯后髋臼周围皮质骨和松质骨的负荷传递机制及应力模式。我们引入了一种计算机断层扫描(CT)辅助骨密度测定的新方法。

方法

我们对26例(26髋)骨关节炎患者进行了研究,在植入后10天内及术后平均1.1年时进行常规序贯CT检查。测量全骨、松质骨和皮质骨的骨密度(mgCaHA/mL)。

结果

随访时,髋臼杯上方皮质骨的平均骨密度值增加了3.6%(p = 0.03),而松质骨密度下降了18%。髋臼杯前方区域的松质骨丢失(-35%)比后方区域(-30%)更大。髋臼杯下方皮质骨密度下降(-6.4%)。所有这些变化均具有统计学意义。髋臼杯后方皮质区域的骨密度变化不显著。

解读

所提出的方法是详细测量全髋关节置换术后髋臼杯周围骨密度变化的极佳工具,并且能够在体内全面评估应力遮挡现象。半球形钛合金压配式髋臼杯是一种刚性植入物,它会使松质骨产生应力遮挡,并增强向髋臼杯上方皮质骨的负荷传递。进一步的研究将证明这些因素对植入物长期结果的影响,并可能实现与假体类型相关的可预测寿命预后。

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