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[睾丸先天性囊性幼年型颗粒细胞瘤。男性新生儿阴囊占位性病变]

[Congenital cystic juvenile granulosa cell tumor of the testes. Scrotal space-occupying lesion in a male neonate].

作者信息

Zugor V, Dimmler A, Engehausen D G, Schott G E

机构信息

Urologische Klinik mit Poliklinik, Friedrich-Alexander-Universität Erlangen-Nürnberg, Krankenhausstrasse 12, 91054, Erlangen, Germany.

出版信息

Urologe A. 2006 Oct;45(10):1312-5. doi: 10.1007/s00120-006-1095-6.

Abstract

This article reports on a newborn with a scrotal space-occupying lesion and histologically proven granulosa cell tumor of the testes. A massive scrotal space-occupying lesion was diagnosed in a full-term male neonate with a birth weight of 2,260 g and body length of 45 cm. Sonography of the right testicle revealed a mass 6x6x4 cm in size which was multiply septate and cystic. The testicular parenchyma was poorly defined with a Swiss cheese appearance. Chemical analysis of blood serum evidenced normal levels of testosterone, beta-HCG, and inhibin B as well as physiologically a clearly elevated alpha-fetoprotein level at 35,350 ng/ml. Based on the clinical and sonographic findings of the right testicle, inguinal surgical exposure of the testes was undertaken. Since there was hardly any testicular parenchyma, we decided to perform high inguinal ablation of the right testicle. This case report confirms that congenital granulosa cell tumors usually exhibit benign behavior during the neonatal period.

摘要

本文报道了一名患有阴囊占位性病变且经组织学证实为睾丸颗粒细胞瘤的新生儿。一名足月男婴被诊断出患有巨大阴囊占位性病变,出生体重2260克,身长45厘米。右侧睾丸超声检查显示一个大小为6×6×4厘米的肿块,呈多房分隔且为囊性。睾丸实质界限不清,呈瑞士奶酪样外观。血清化学分析显示睾酮、β-HCG和抑制素B水平正常,而甲胎蛋白水平在生理上明显升高,达35350纳克/毫升。基于右侧睾丸的临床和超声检查结果,对睾丸进行了腹股沟手术暴露。由于几乎没有睾丸实质,我们决定对右侧睾丸进行高位腹股沟切除术。本病例报告证实先天性颗粒细胞瘤在新生儿期通常表现为良性行为。

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