Hoekstra M O, Meijer Y, Pasmans S G M A, Knulst A C
Afd. Dermatologie, Universitair Medisch Centrum Utrecht, Wilhelmina Kinderziekenhuis, Centrum voor Kinderallergologie, Postbus 85.090, 3508 AB Utrecht.
Ned Tijdschr Geneeskd. 2006 Jun 10;150(23):1278-80.
Every child with possible food allergies has the right to a double-blind, placebo-controlled cow's milk challenge. This test can be performed in the paediatric ward of a non-academic hospital. Challenge with other foodstuffs can lead to more serious side effects and therefore should be considered in a general hospital setting only after extensive experience with double-blind, placebo-controlled challenge for cow's milk has been obtained. Other items of international discussion on double-blind, placebo-controlled challenge in children are: the natural development of tolerance for cow's milk, IgE- versus non-IgE-mediated cow's milk allergy, and the exacerbation of pre-existing eczema during and after double-blind, placebo-controlled challenge.
每个可能患有食物过敏的儿童都有权接受双盲、安慰剂对照的牛奶激发试验。该试验可在非学术性医院的儿科病房进行。对其他食物进行激发试验可能会导致更严重的副作用，因此，只有在获得了对牛奶进行双盲、安慰剂对照激发试验的丰富经验之后，才应在综合医院环境中考虑进行。国际上关于儿童双盲、安慰剂对照激发试验的其他讨论内容包括：牛奶耐受性的自然发展、IgE介导与非IgE介导的牛奶过敏，以及双盲、安慰剂对照激发试验期间及之后原有湿疹的加重情况。
