Suppr超能文献

福尼尔坏疽。早期诊断和多模式治疗是取得成功预后的基石。

Fournier's gangrene. Immediate diagnosis and multimodality treatment is the comerstone for successful outcome.

作者信息

Rizos Spiros, Filippou Dimitrios K, Condilis Nicolas, Filippou Georgios, Trigka Argiro, Skandalakis Panagiotis, Vezakis Antonios

机构信息

Department of Surgery, Kifissias Anticancer Hospital Agii Anargiri, Athens, Greece.

出版信息

Ann Ital Chir. 2005 Nov-Dec;76(6):563-7.

Abstract

BACKGROUND

Fournier's gangrene is a synergistic necrotic fasciitis or myositis of genitalia, perineum and abdominal wall. Several etiologic factors have been reported, microorganisms isolated and co-morbidity factors identified. Immediate and accurate diagnosis decreases mortality rate, which ranges from 3-67%. Aggressive resuscitation and surgical debridement consist the appropriate treatment.

MATERIAL AND METHODS

Six cases of Fournier's gangrene treated the last ten years were reviewed. Three of them presented with mild infection while the other three with severe. The mean time interval between first symptoms and initial treatment was 2.1 days. The diagnosis was set immediately and the treatment included fluid-electrolyte resuscitation, aggressive surgical debridement, and broad-spectrum antibiotics administration.

RESULTS

All patients survived. The defects healed by second intention in four patients and only in two patients specific plastic reconstructive techniques were required. Hyperbaric oxygenation administrated in one patient induced surprisingly the healing of the lesion.

CONCLUSIONS

The Authors confirm that Fournier's gangrene is a rare and potentially fatal disease. Early suspicion, accurate diagnosis and multimodality treatment including aggressive surgical intervention are essential for successful outcome.

摘要

背景

福尼尔坏疽是一种累及生殖器、会阴和腹壁的协同性坏死性筋膜炎或肌炎。已有多种病因、分离出的微生物及合并症因素的报道。及时准确的诊断可降低死亡率,死亡率在3%至67%之间。积极的复苏和手术清创是恰当的治疗方法。

材料与方法

回顾过去十年间治疗的6例福尼尔坏疽病例。其中3例为轻度感染,另外3例为重度感染。首次症状出现至初始治疗的平均时间间隔为2.1天。诊断立即明确,治疗包括液体电解质复苏、积极的手术清创和广谱抗生素的应用。

结果

所有患者均存活。4例患者通过二期愈合,仅2例患者需要特定的整形重建技术。1例患者接受高压氧治疗后病变意外愈合。

结论

作者证实福尼尔坏疽是一种罕见且潜在致命的疾病。早期怀疑、准确诊断以及包括积极手术干预在内的多模式治疗对于取得成功的治疗结果至关重要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验