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[位于上颌骨的骨纤维异常增殖症——病例报告展示的诊断与治疗难点]

[Fibrous dysplasia situated in maxilla--diagnostic and treatment difficulties illustrated with case report].

作者信息

Reymond Jerzy, Podsiadło Maciej, Wyskiel Maciej

机构信息

Oddział Chirurgii Szczekowo-Twarzowej Radomskiego Szpitala Specjalistycznego.

出版信息

Otolaryngol Pol. 2006;60(1):79-84.

Abstract

INTRODUCTION

Fibrous dysplasia is a benign and slowly progressing pathological disorder of bone, in which normal cancellous bone is replaced by immature woven bone and fibrous tissue. The disease is rare and its etiology is unknown.

MATERIAL AND METHODS

On the base of literature review the clinical, radiological and microscopical characteristics of the disease was presented. For illustration of prolongation of this process and the diagnostic and therapeutic difficulties encountered in this disease a single case of dysplasia fibrosa was presented also. This is the case of 28 year old man, who is in follow-up for 18 years.

RESULTS

In clinical investigation a relief of left malar region and left cheek. In mouth cavity swelling of left maxillary process was observed as well as anterior wall of maxillary sinus. All teeth were in good condition. In CT investigation irregular bone thickenings of anterior and lateral walls of maxillary sinus were visible. In general anesthesia a plastic surgery of the maxilla was performed. In histopathology was observed typical picture of fibrous dysplasia.

CONCLUSIONS

As a conclusion of this work we would like to state that fibrous dysplasia occurs mainly in young people; clinical and radiological signs of fibrous dysplasia are not sufficient to diagnose this disease: the most important is histopathology result; operative treatment of fibrous dysplasia in a way of tissue modeling allows for restoration of symmetrical face view, but never goes to full healing.

摘要

引言

骨纤维异常增殖症是一种良性且进展缓慢的骨病理紊乱疾病,其中正常的松质骨被未成熟的编织骨和纤维组织所取代。该疾病罕见,病因不明。

材料与方法

在文献综述的基础上,阐述了该疾病的临床、放射学和显微镜特征。为说明这一病程的迁延以及该疾病所遇到的诊断和治疗困难,还介绍了一例骨纤维异常增殖症病例。这是一名28岁男性患者,已随访18年。

结果

临床检查发现左侧颧骨区域和左侧脸颊缓解。口腔内可见左上颌突及上颌窦前壁肿胀。所有牙齿状况良好。CT检查可见上颌窦前壁和外侧壁不规则骨质增厚。在全身麻醉下对上颌骨进行了整形手术。组织病理学观察到骨纤维异常增殖症的典型表现。

结论

作为这项工作的结论,我们想说骨纤维异常增殖症主要发生在年轻人中;骨纤维异常增殖症的临床和放射学征象不足以诊断该疾病:最重要的是组织病理学结果;以组织塑形方式对骨纤维异常增殖症进行手术治疗可恢复面部对称外观,但无法完全治愈。

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