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肛门直肠畸形相关先天性异常的发生率。

Incidence of associated congenital anomalies in anorectal malformations.

作者信息

Saha Subodh Ranjan, Roy Ashoke Kumar, Saha Sujitesh

机构信息

Department of Paediatric Surgery, NRS Medical College, Kolkata 700014.

出版信息

J Indian Med Assoc. 2005 Dec;103(12):690-1.

Abstract

The study was undertaken to review the incidence and types of associated congenital urogenital anomalies in patients with anorectal malformations (ARM) and compare the results with previously published world literature. Retrospective review was done of 220 cases of ARM, treated during May 2002 to April 2003. All patients routinely underwent ultrasound study of the KUB region and pelvis and lumbosacral radiography. Voiding cystourethrography, nuclear renography and other investigations like buccal smear and karyotyping were done in selected cases only. Genital anomalies were found in 30 cases (13.63%) and urologic anomalies in 25 cases (11.36%), a direct correlation being found between the level of ARM and the incidence of urogenital anomalies. The high incidence of associated anomalies (24.54%) makes careful clinical examination and evaluation of the urinary tract during the neonatal or early infantile period mandatory in all cases of ARM, particularly to avoid deterioration of renal function in future.

摘要

本研究旨在回顾肛门直肠畸形(ARM)患者相关先天性泌尿生殖系统异常的发生率及类型,并将结果与此前发表的世界文献进行比较。对2002年5月至2003年4月期间治疗的220例ARM病例进行了回顾性研究。所有患者均常规接受了腹部平片(KUB)区域及骨盆的超声检查以及腰骶部X线摄影。仅在部分病例中进行了排尿性膀胱尿道造影、核素肾显像以及其他检查,如颊黏膜涂片和染色体核型分析。发现30例(13.63%)存在生殖器异常,25例(11.36%)存在泌尿系统异常,且发现ARM的程度与泌尿生殖系统异常的发生率之间存在直接关联。相关异常的高发生率(24.54%)使得对所有ARM病例在新生儿期或婴儿早期进行仔细的临床检查和泌尿系统评估成为必要,尤其是为了避免未来肾功能恶化。

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