Timmons Otwell
Carolinas Medical Center, Charlotte, NC 28203, USA.
Semin Pediatr Infect Dis. 2006 Apr;17(2):65-71. doi: 10.1053/j.spid.2006.04.004.
Pediatric acute respiratory distress syndrome (ARDS) is a severe lung injury caused by pneumonia, sepsis, and trauma. ARDS results from inflammation and pulmonary capillary leak causing major changes in lung architecture and function. It has a low incidence, but its severity and duration cause major morbidity, mortality, and use of resources. Any organism can cause ARDS. Susceptible populations develop the syndrome more often and have worse outcomes. Aggressive diagnosis and intensive treatment are essential to good outcomes in ARDS caused by infection. The prognosis for survival is good, but morbidity after the syndrome is a major burden.
小儿急性呼吸窘迫综合征（ARDS）是由肺炎、脓毒症和创伤引起的严重肺损伤。ARDS是由炎症和肺毛细血管渗漏导致肺结构和功能发生重大变化所致。其发病率较低，但其严重程度和持续时间会导致严重的发病、死亡和资源消耗。任何生物体都可引起ARDS。易感人群更常发生该综合征且预后较差。对于感染所致的ARDS，积极诊断和强化治疗对于取得良好预后至关重要。生存预后良好，但该综合征后的发病是一个主要负担。
