Sterzer Philipp, Haynes John-Dylan, Rees Geraint
Wellcome Department of Imaging Neuroscience, University College London, 12 Queen Square, London WC1N 3BG, UK.
Neuroimage. 2006 Sep;32(3):1308-16. doi: 10.1016/j.neuroimage.2006.05.029. Epub 2006 Jul 5.
Apparent motion (AM) is the illusory perception of real motion created when two spatially distinct stationary visual objects are presented in alternating sequence. In common with many other illusory percepts, activation during AM can be identified in unstimulated regions of V1 representing the illusory motion path. However, little is known about the mechanisms underlying such activation and its relationship with motion-sensitive area hMT+/V5. Using fMRI and a novel AM stimulus, we replicated previous findings showing a correlate of the perceived AM path in V1. To more closely characterize the mechanisms underlying these activations, we performed analyses of effective connectivity and found that the AM-induced activations on the illusory AM path were associated with enhanced feedback (but not feedforward) connectivity from hMT+/V5. These findings provide for the first time evidence for the involvement of cortico-cortical coupling in generating an illusory percept of AM. They therefore emphasize the role of recurrent processing between visual cortical areas in human perceptual awareness.
表观运动（AM）是指当两个空间上不同的静止视觉对象以交替顺序呈现时产生的真实运动的错觉感知。与许多其他错觉感知一样，在代表错觉运动路径的V1未受刺激区域中可以识别出AM期间的激活。然而，对于这种激活的潜在机制及其与运动敏感区域hMT+/V5的关系知之甚少。我们使用功能磁共振成像（fMRI）和一种新型的AM刺激，重复了先前的研究结果，即在V1中发现了与感知到的AM路径相关的激活。为了更精确地描述这些激活背后的机制，我们进行了有效连接性分析，发现错觉AM路径上的AM诱导激活与来自hMT+/V5的增强反馈（而非前馈）连接有关。这些发现首次为皮质-皮质耦合参与产生AM错觉感知提供了证据。因此，它们强调了视觉皮层区域之间的循环处理在人类感知意识中的作用。
