Sharma R, Shivanand G, Kumar R, Prem S, Kandpal H, Das C J, Sharma M C
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi-110029, India.
Br J Radiol. 2006 Jul;79(943):e19-21. doi: 10.1259/bjr/17821080.
Mucormycosis is an opportunistic fungal infection occurring most often in immunocompromised patients. The most common clinical presentation of infection with the fungus is rhinocerebral, followed by primary pulmonary, disseminated, gastrointestinal and cutaneous manifestations. Renal involvement in disseminated mucormycosis is well described, however, there are only few case reports describing the isolated renal mucormycosis in literature. We present an unusual case of renal mucormycosis in a patient of aplastic anaemia who presented with right flank pain and, on imaging, was found to have renal infarction and thrombosis of renal vessels. Histopathology revealed fungal hyphae infiltrating the entire kidney, renal vessels and perinephric space.
毛霉病是一种机会性真菌感染，最常发生于免疫功能低下的患者。该真菌感染最常见的临床表现为鼻脑型，其次是原发性肺型、播散型、胃肠道型和皮肤型表现。播散性毛霉病累及肾脏的情况已有充分描述，然而，文献中仅有少数病例报告描述了孤立性肾毛霉病。我们报告一例再生障碍性贫血患者发生肾毛霉病的罕见病例，该患者表现为右侧胁腹疼痛，影像学检查发现有肾梗死和肾血管血栓形成。组织病理学检查显示真菌菌丝浸润整个肾脏、肾血管和肾周间隙。
