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再生障碍性贫血患者侵袭性真菌感染的当前应对策略：力强而器不利，一例病例报告及文献综述

Current strategies against invasive fungal infections in patients with aplastic anemia, strong power and weak weapon, a case report and review of literature.

作者信息

Zekavat Omid Reza, Amanati Ali, Saleh Fazl, Abdolkarimi Babak, Fathpour Gholamreza, Badiee Parisa, Geramizadeh Bita

机构信息

Hematology Research Center, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran; Department of Pediatric Oncology, Amir Oncology Hospital, Farhang Shahr, Shiraz 7187915998, Iran.

Professor Alborzi Clinical Microbiology Research Center, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran; Department of Pediatric Infectious Diseases, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran.

出版信息

Med Mycol Case Rep. 2016 Mar 8;11:16-20. doi: 10.1016/j.mmcr.2016.03.003. eCollection 2016 Mar.

DOI:10.1016/j.mmcr.2016.03.003
PMID:27047751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4796718/
Abstract

We report an 18 year old boy with Aplastic anemia complicated by serious fungal rhinosinusitis. Despite prompt treatment and early repeated surgical debridements, he died after about more than 6 weeks of hard challenges with fungal infections. Current strategies against invasive fungal infections (IFIs) in patients with Aplastic anemia may be inadequate for the management of serious complications. Antifungal prophylaxis is highly recommended in pre-transplant period for severe form of Aplastic anemia.

摘要

我们报告了一名18岁患有再生障碍性贫血并并发严重真菌性鼻-鼻窦炎的男孩。尽管进行了及时治疗和早期反复手术清创，但在与真菌感染进行了约6周多的艰难抗争后，他还是去世了。目前针对再生障碍性贫血患者侵袭性真菌感染（IFI）的策略可能不足以应对严重并发症的管理。对于重型再生障碍性贫血患者，强烈建议在移植前期进行抗真菌预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/2f945a7a2426/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/c637e6f50635/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/24a863bf6178/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/8bb0e4ef89d0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/79930e5cfbca/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/2f945a7a2426/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/c637e6f50635/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/24a863bf6178/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/8bb0e4ef89d0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/79930e5cfbca/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc5f/4796718/2f945a7a2426/gr5.jpg

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本文引用的文献

1
Evaluation of nested PCR in diagnosis of fungal rhinosinusitis.巢式聚合酶链反应在真菌性鼻-鼻窦炎诊断中的应用评估
Iran J Microbiol. 2015 Feb;7(1):62-6.
2
The diagnosis and treatment of aplastic anemia: a review.再生障碍性贫血的诊断与治疗：综述
Int J Hematol. 2015 Jun;101(6):527-35. doi: 10.1007/s12185-015-1787-z. Epub 2015 Apr 3.
3
Lingual necrosis caused by mucormycosis in a patient with aplastic anaemia: case report.再生障碍性贫血患者毛霉菌病引起的舌坏死：病例报告
Br J Oral Maxillofac Surg. 2014 Dec;52(10):e144-6. doi: 10.1016/j.bjoms.2014.09.012. Epub 2014 Oct 7.
4
Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients with cancer or allogeneic haemopoietic stem-cell transplantation.第四届欧洲白血病感染会议（ECIL-4）：儿童癌症或异基因造血干细胞移植患者侵袭性真菌感染的诊断、预防和治疗指南。
Lancet Oncol. 2014 Jul;15(8):e327-40. doi: 10.1016/S1470-2045(14)70017-8.
5
Evaluation of noninvasive methods for the diagnosis of fungal endocarditis.真菌性心内膜炎的无创诊断方法评估。
Med Mycol. 2014 Jul;52(5):530-6. doi: 10.1093/mmy/myu017. Epub 2014 Jun 9.
6
ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormycosis 2013.ESCMID 和 ECMM 联合临床指南：2013 年毛霉病的诊断和管理
Clin Microbiol Infect. 2014 Apr;20 Suppl 3:5-26. doi: 10.1111/1469-0691.12371.
7
A risk prediction score for invasive mold disease in patients with hematological malignancies.血液恶性肿瘤患者侵袭性霉菌病的风险预测评分。
PLoS One. 2013 Sep 26;8(9):e75531. doi: 10.1371/journal.pone.0075531. eCollection 2013.
8
Fungal arthritis of the hip in patient with aplastic anaemia.再生障碍性贫血患者的髋关节真菌性关节炎。
BMJ Case Rep. 2013 Aug 13;2013:bcr2013008902. doi: 10.1136/bcr-2013-008902.
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Invasive fungal infections in acute leukemia.急性白血病的侵袭性真菌感染。
Ther Adv Hematol. 2011 Aug;2(4):231-47. doi: 10.1177/2040620711410098.
10
Rhino-orbital-cerebral mucormycosis.鼻-眶-脑毛霉病。
Curr Infect Dis Rep. 2012 Aug;14(4):423-34. doi: 10.1007/s11908-012-0272-6.