Nilsson Kjell G, Henricson Anders, Norgren Bo, Dalén Tore
Department of Orthopaedics, Umeå University Hospital, Sweden.
Clin Orthop Relat Res. 2006 Jul;448:129-39. doi: 10.1097/01.blo.0000224003.33260.74.
Fixation of the tibial component in total knee arthroplasty in younger patients remains controversial. We evaluate the results of three different types of fixation of the Profix total knee arthroplasty in a randomized controlled trial of 97 consecutive knees (85 patients) with osteoarthrosis or inflammatory arthritis with 2-year followup of all patients. We randomized patients to three different types of fixation of the tibial component: cemented, uncemented (HA coated) with screws, or uncemented (HA coated) without screws. We performed clinical evaluations and radiostereometric analysis at 6 weeks, and 3, 6, 12 and 24 months postoperatively. The knees in the uncemented groups migrated more than those in the cemented group during the first 3 months, but at 2 years we observed no differences. The uncemented implants displayed all migration within the first 3 months. The cemented implants did not stabilize but had continuously increasing migration during the followup. Cementless implants without screws did not migrate more than implants with screws and displayed similar pattern of migration, indicating screws do not improve fixation. Uncemented fixation using hydroxyapatite-coated implants without screws seems to be the best solution for the younger patient.
Therapeutic Level I. See the Guidelines for Authors for a complete description of levels of evidence.
在年轻患者的全膝关节置换术中,胫骨假体的固定仍存在争议。在一项针对97例连续膝关节(85例患者)骨关节炎或炎性关节炎患者的随机对照试验中,我们对Profix全膝关节置换术的三种不同固定类型的结果进行了评估,所有患者均随访2年。我们将患者随机分为胫骨假体的三种不同固定类型:骨水泥固定、带螺钉的非骨水泥(羟基磷灰石涂层)固定或不带螺钉的非骨水泥(羟基磷灰石涂层)固定。我们在术后6周、3个月、6个月、12个月和24个月进行了临床评估和放射立体测量分析。在最初3个月内,非骨水泥组的膝关节移位比骨水泥组更多,但在2年时我们未观察到差异。非骨水泥假体在最初3个月内出现了所有移位。骨水泥假体未稳定,而是在随访期间移位持续增加。不带螺钉的非骨水泥假体移位并不比带螺钉的假体多,且显示出相似的移位模式,表明螺钉并不能改善固定。对于年轻患者,使用无螺钉的羟基磷灰石涂层假体进行非骨水泥固定似乎是最佳解决方案。
治疗性I级。有关证据水平的完整描述,请参阅作者指南。