葡萄牙铁线莲中两种黄酮醇苷的1,1-二苯基-2-三硝基苯肼自由基清除活性
DPPH radical scavenging activity of two flavonol glycosides from Aconitum napellus sp. lusitanicum.
作者信息
Luis J C, Valdés F, Martín R, Carmona A J, Díaz Jesús G
机构信息
Facultad de Farmacia, Departamento de Biología Vegetal y Fisiología Vegetal, Universidad de La Laguna, Avenida Astrofísico Francisco Sánchez s/n, C. P. 38206, La Laguna, Tenerife, Spain.
出版信息
Fitoterapia. 2006 Sep;77(6):469-71. doi: 10.1016/j.fitote.2006.05.018. Epub 2006 May 25.
The DPPH radical scavenging activity of two flavonol glycosides obtained from ethanolic extracts of Aconitum napellus sp. lusitanicum was studied. The results showed a high DPPH antiradical activity of compound 1 (quercetin 3-O-(6-trans-caffeoyl)-beta-glucopyranosyl-(1-->2)-beta-glucopyranosyl-7-O-alpha-rhamnopyranoside) when compared with compound 2 (quercetin-3-sophoroside-7-rhamnopyranoside), rutin and ascorbic acid. The relationship between the caffeoyl and rhamnopyranoside groups in the flavonol glycosides structures and the DPPH antiradical activity was also discussed.
研究了从葡萄牙铁线莲乙醇提取物中获得的两种黄酮醇苷的1,1-二苯基-2-三硝基苯肼（DPPH）自由基清除活性。结果表明，与化合物2（槲皮素-3-槐糖苷-7-鼠李糖苷）、芦丁和抗坏血酸相比，化合物1（槲皮素3-O-(6-反式-咖啡酰基)-β-吡喃葡萄糖基-(1→2)-β-吡喃葡萄糖基-7-O-α-鼠李吡喃糖苷）具有较高的DPPH抗自由基活性。还讨论了黄酮醇苷结构中咖啡酰基和鼠李吡喃糖苷基团与DPPH抗自由基活性之间的关系。
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