Frank Linda A
Diplomate American College of Veterinary Dermatology, The University of Tennessee, College of Veterinary Medicine, Knoxville, TN 37996-4544, USA.
Clin Dermatol. 2006 Jul-Aug;24(4):317-25. doi: 10.1016/j.clindermatol.2006.04.007.
Endocrine diseases in the dog commonly manifest with dermatological lesions. Hypothyroidism is the most common endocrinopathy and usually presents with alopecia in areas of wear, seborrhea, and recurrent infections. Common clinical signs associated with hyperadrenocorticism include polyuria, polydipsia, and polyphagia. The most common dermatological manifestation of hyperadrenocorticism is bilaterally symmetrical alopecia sparing the head and distal extremities. Pyoderma is a common finding associated with immunosuppression. Less commonly, calcinosus cutis may occur. Sex hormone excess, primarily hyperestrogenism and hyperandrogenism, may also be associated with dermatological signs. Usually, dogs are intact, and the excess production is due to testicular or ovarian neoplasia.
犬类内分泌疾病通常表现为皮肤病变。甲状腺功能减退是最常见的内分泌病,通常表现为易磨损部位脱毛、皮脂溢和反复感染。与肾上腺皮质功能亢进相关的常见临床症状包括多尿、多饮和多食。肾上腺皮质功能亢进最常见的皮肤表现是双侧对称性脱毛,头部和四肢远端除外。脓皮病是与免疫抑制相关的常见症状。较少见的情况下,可能会发生皮肤钙质沉着。性激素过多,主要是雌激素过多和雄激素过多,也可能与皮肤症状有关。通常,犬类未绝育,激素过量产生是由于睾丸或卵巢肿瘤。