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创伤性腘血管损伤患者的肢体挽救及预后:国家创伤数据库分析

Limb salvage and outcomes among patients with traumatic popliteal vascular injury: an analysis of the National Trauma Data Bank.

作者信息

Mullenix Philip S, Steele Scott R, Andersen Charles A, Starnes Benjamin W, Salim Ali, Martin Matthew J

机构信息

General Surgery Service, Madigan Army Medical Center, Tacoma, WA 98431-1100, USA.

出版信息

J Vasc Surg. 2006 Jul;44(1):94-100. doi: 10.1016/j.jvs.2006.02.052.

Abstract

PURPOSE

Popliteal arterial trauma carries the greatest risk of limb loss of any peripheral vascular injury. The purpose of this study was to analyze outcomes after popliteal arterial injuries and identify factors contributing to disability.

METHODS

A retrospective analysis was conducted of prospectively collected trauma data from the National Trauma Data Bank (NTDB). We studied all patients with popliteal arterial injury in terms of demographics, injury patterns, interventions, limb salvage, resource utilization, and outcomes.

RESULTS

We identified 1395 popliteal arterial injuries among the 1,130,000 patients in the NTDB, for an incidence <0.2%. The patients were 82% male, with a mean age of 33 years, and they presented with a mean initial systolic blood pressure of 124 mm Hg, base deficit -4.6, injury severity score of 11.8, and an extremity abbreviated injury score of 2.6. The mechanism was blunt in 61% and penetrating in 39%, and significant baseline demographic differences existed between the two groups. Associated ipsilateral lower-extremity trauma included combined popliteal arterial and venous (AV) injuries, fractures and dislocations, and major nerve disruptions. Fasciotomies were performed in 49%, complex soft tissue repairs in 24%, and amputations in 14.5%. The overall mean hospital and intensive care unit lengths of stay were 16.9 and 5.9 days. The mean functional independence measure for locomotion was 2.8, but was significantly lower for patients with blunt trauma. In-hospital mortality was 4.5% and did not significantly differ by mechanism. Amputation rates were 15% with combined AV injuries, 21% for associated nerve injuries, 12% for major soft tissue disruptions, and 21% for femur, 12% for knee, and 20% for tibia-fibula fractures or dislocations. Among the 312 patients with combined AV injuries, those with blunt mechanism had a significantly higher amputation rate than those with penetrating injury (27% vs 9%, P < .001). Adjusting for age, gender, mechanism, and overall physiologic impact of injuries sustained, independent predictors of amputation in logistic regression analysis of the entire cohort included fracture (odds ratio [OR], 2.4; 95% confidence interval [CI], 1.4 to 4.1), complex soft tissue injury (OR, 1.9; 95% CI, 1.2 to 3.0), nerve injury (OR, 1.7; 95% CI, 1.1 to 2.8), and extremity abbreviated injury score (OR, 1.6; 95% CI, 1.2 to 2.2).

CONCLUSIONS

Popliteal vascular injury remains an uncommon but challenging clinical entity associated with significant rates of limb loss, functional disability, and mortality. Blunt vs penetrating mechanism and associated musculoskeletal injuries generally involve longer hospital stays, worse functional outcomes, and twice the amputation rate.

摘要

目的

在所有外周血管损伤中,腘动脉创伤导致肢体丧失的风险最大。本研究的目的是分析腘动脉损伤后的结局,并确定导致残疾的因素。

方法

对前瞻性收集的来自国家创伤数据库(NTDB)的创伤数据进行回顾性分析。我们从人口统计学、损伤模式、干预措施、肢体挽救、资源利用和结局等方面研究了所有腘动脉损伤患者。

结果

在NTDB的1130000例患者中,我们识别出1395例腘动脉损伤,发病率<0.2%。患者中82%为男性,平均年龄33岁,初始平均收缩压为124mmHg,碱缺失-4.6,损伤严重程度评分为11.8,肢体简明损伤评分为2.6。损伤机制为钝性伤的占61%,穿透伤的占39%,两组之间存在显著的基线人口统计学差异。同侧下肢相关创伤包括腘动脉和静脉联合损伤(AV)、骨折和脱位以及主要神经损伤。49%的患者进行了筋膜切开术,24%进行了复杂软组织修复,14.5%进行了截肢。总体平均住院时间和重症监护病房住院时间分别为16.9天和5.9天。运动功能独立测量的平均值为2.8,但钝性创伤患者明显更低。住院死亡率为4.5%,不同损伤机制之间无显著差异。AV联合损伤的截肢率为15%,相关神经损伤为21%,严重软组织损伤为12%,股骨骨折为21%,膝关节损伤为12%,胫腓骨骨折或脱位为20%。在312例AV联合损伤患者中,钝性损伤机制的患者截肢率显著高于穿透伤患者(27%对9%,P<.001)。在对整个队列进行逻辑回归分析时,在调整年龄、性别、损伤机制和所受损伤的总体生理影响后,截肢的独立预测因素包括骨折(比值比[OR],2.4;95%置信区间[CI],1.4至4.1)、复杂软组织损伤(OR,1.9;95%CI,1.2至3.0)、神经损伤(OR,1.7;95%CI,1.1至2.8)和肢体简明损伤评分(OR,1.6;95%CI,1.2至2.2)。

结论

腘血管损伤仍然是一种罕见但具有挑战性的临床病症,与较高的肢体丧失、功能残疾和死亡率相关。钝性伤与穿透伤机制以及相关的肌肉骨骼损伤通常涉及更长的住院时间、更差的功能结局以及两倍的截肢率。

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