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经皮腔内冠状动脉旋磨术治疗川崎病所致局限性狭窄

Percutaneous transluminal coronary rotational atherectomy for localized stenosis caused by Kawasaki disease.

作者信息

Tsuda Etsuko, Miyazaki Syunichi, Yamada Osamu, Takamuro Motoki, Takekawa Tsuyoshi, Echigo Shigeyuki

机构信息

Department of Pediatrics, National Cardiovascular Center, Suita-shi, Osaka, Japan.

出版信息

Pediatr Cardiol. 2006 Jul-Aug;27(4):447-53. doi: 10.1007/s00246-006-1276-5. Epub 2006 Jul 6.

Abstract

We report the results of percutaneous transluminal coronary rotational atherectomy (PTCRA) for localized stenosis caused by Kawasaki disease (KD) in children. Five males and a females, aged 5-15 years old (median, 9), underwent PTCRA. The interval from the onset of KD to PTCRA ranged from 5 to 12 years (median, 9). The target vessels were the left anterior descending artery (three patients), the left circumflex (two patients), and the right coronary artery (one patient). The immediate results of PTCRA were successful in all patients, and the mean stenosis degree improved from 89 +/- 10% to 27 +/- 12%. In follow-up coronary angiograms within 1 year, four vessels were restenosed, including two with complete occlusion. A 15-year-old male has had good patency for 4 years after undergoing re-PTCRA for restenosis using a larger burr size. PTCRA is feasible for severe localized stenosis with calcification caused by KD in children and the immediate results are good. However, restenosis often occurred within 1 year after PTCRA in small children and PTCRA is not always appropriate for them. When the use of a larger burr is possible, good patency can be expected and can be maintained by close follow-up and re-PTCRA.

摘要

我们报告了经皮腔内冠状动脉旋磨术(PTCRA)治疗儿童川崎病(KD)所致局限性狭窄的结果。5名男性和1名女性,年龄5 - 15岁(中位数为9岁),接受了PTCRA。从KD发病到PTCRA的间隔时间为5至12年(中位数为9年)。靶血管为左前降支(3例患者)、左旋支(2例患者)和右冠状动脉(1例患者)。PTCRA的即刻结果在所有患者中均成功,平均狭窄程度从89±10%改善至27±12%。在1年内的随访冠状动脉造影中,4支血管发生再狭窄,其中2支完全闭塞。一名15岁男性在因再狭窄接受再次PTCRA(使用更大尺寸的磨头)后4年保持了良好的血管通畅。PTCRA对于儿童KD所致伴有钙化的严重局限性狭窄是可行的,且即刻结果良好。然而,小儿PTCRA后1年内常发生再狭窄,PTCRA对他们并不总是合适的。当可以使用更大尺寸的磨头时,通过密切随访和再次PTCRA有望获得并维持良好的血管通畅。

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