镰状细胞贫血患者的慢性肝病。

Chronic liver disease in a patient with sickle cell anemia.

作者信息

Savafi Nurten Akyürek, Akbulut Sabiye, Köseoglu Tankut, Albayrak Levent

机构信息

Departments of Gastroenterology, Ankara Numune Training and Research Hospital, Ankara, Turkey.

出版信息

Turk J Gastroenterol. 2006 Jun;17(2):123-5.

PMID:16830296

Abstract

Various disorders of the hepatobiliary system can occur due to sickling in patients with sickle cell anemia. Pathology and frequency of these disorders are not clearly known. Liver biopsies of these patients show erythrocytosis, erythrophagocytosis, sinusoidal dilatation and hyperplasia in Kupffer cells. We present a 21-year-old male patient diagnosed with sickle cell anemia who developed chronic liver disease, together with a review of the literature.

摘要

镰状细胞贫血患者由于镰状化可出现各种肝胆系统疾病。这些疾病的病理学及发生率尚不清楚。对这些患者进行肝脏活检可发现红细胞增多、噬红细胞现象、肝血窦扩张以及库普弗细胞增生。我们报告了一例21岁诊断为镰状细胞贫血并发展为慢性肝病的男性患者，并对相关文献进行了综述。