一名艾滋病患者的阿昔洛韦耐药性生殖器疱疹病毒感染
Acyclovir resistant genital herpes virus infection in a patient with AIDS.
作者信息
Marrero M, Alvarez M, Millan J C, Mas Lago P, Soler M, Diaz M
机构信息
Department of Virology, Institute of Tropical Medicine, Pedro Kouri, Havana City, Cuba.
出版信息
Acta Virol. 1991 Jan;35(1):86-9.
PMID:1683121
Abstract
Three acyclovir resistant strains of HSV-2 were isolated from mucoulcerative lesions in a patient suffering from AIDS in whom the oral and intravenous acyclovir treatment was unsuccessful. All the isolates were classified by monoclonal antibodies and showed no differences in DNA restriction patterns.
摘要
从一名患有艾滋病的患者的黏膜溃疡性病变中分离出三株对阿昔洛韦耐药的单纯疱疹病毒2型毒株，该患者接受口服和静脉注射阿昔洛韦治疗均未成功。所有分离株均通过单克隆抗体进行分类，并且在DNA限制性图谱上没有差异。
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