Bastow D, Rawlings J, Allison S P
University Hospital, Queens Medical Centre, Nottingham NG7 2UH, U.K.
Clin Nutr. 1985 Feb;4(1):7-11. doi: 10.1016/0261-5614(85)90031-7.
Overnight nasogastric tube feeding allows the patient freedom for normal daytime activities and exercise, essential components of rehabilitation. In order to avoid disturbed nights through frequent micturition we have kept the volume of feed to a minimum. Two types of feed have been used: 1. A supplementary isosmolar feed containing 1000 kCals in 1 litre. 2. A concentrated low volume (404 mosm/kg) feed supplying 1800 kCals including 60 g of nitrogen in 1 litre. Both were delivered via a fine bore tube (internal diameter 1 mm) by continuous infusion from a 1-1.5 litre reservoir using a rotary pump. Feed 1 was given to 64 undernourished elderly female patients (group 1) with fractured neck of femur, the tube being tolerated by 78%; 47 patients in this group were fed for more than 5 days. Feed 2 was given to 10 patients in hospital (group 2) and 8 patients at home (group 3). Few side effects were encountered, the hyperosmolar feed causing no diarrhoea, nausea or hyperglycaemia, emphasising the importance of osmoles per unit time rather than per unit volume. Voluntary oral intake was neither impaired nor increased during the period of tube feeding in group 1, in whom anorexia and thinness were longstanding. In group 2, with recent onset of anorexia and weight loss, tube feeding disinhibited appetite, resulting in a doubling of voluntary oral intake. Improvement in anthropometric and biochemical nutritional parameters was seen in all patients. Clinical improvements e.g. closure of fistulae were also observed. This paper describes the results of our trial of both these options in patients treated in hospital or at home.
夜间鼻饲可让患者在白天进行正常活动和锻炼,这些都是康复的重要组成部分。为避免因频繁排尿而影响夜间休息,我们将饲食量减至最低。我们使用了两种类型的饲料:1. 一种补充性等渗饲料,1升含1000千卡热量。2. 一种浓缩低容量(404毫渗量/千克)饲料,1升提供1800千卡热量,包括60克氮。两种饲料均通过内径1毫米的细管,使用旋转泵从1 - 1.5升的储液器中持续输注。饲料1用于64名股骨颈骨折的营养不良老年女性患者(第1组),78%的患者能耐受鼻饲管;该组47名患者的鼻饲时间超过5天。饲料2用于10名住院患者(第2组)和8名在家患者(第3组)。几乎未出现副作用,高渗饲料未引起腹泻、恶心或高血糖,这强调了单位时间而非单位体积的渗透摩尔的重要性。在第1组长期存在厌食和消瘦的患者中,鼻饲期间自主口服摄入量既未受损也未增加。在第2组近期出现厌食和体重减轻的患者中,鼻饲解除了食欲抑制,导致自主口服摄入量增加了一倍。所有患者的人体测量和生化营养参数均有改善。还观察到了临床改善,如瘘管闭合。本文描述了我们对这两种方案在住院或在家治疗的患者中进行试验的结果。