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[使用乳内动脉进行心肌血运重建。适应证、技术及结果]

[Myocardial revascularization with the internal mammary artery. The indications, technics and results].

作者信息

Luciani N, Di Giammarco G, Glieca F, Antico A, Santarelli P, Di Nardo E, Paloscia L, Maddestra N, Battaglini G, Calafiore A M

机构信息

Istituto di Clinica Cardiovascolare, Università di Chieti.

出版信息

Ann Ital Chir. 1991 Jan-Feb;62(1):55-61.

PMID:1683199
Abstract

This report reviews 218 patients who underwent internal mammary artery (IMA) grafting alone or with vein graft between 1986-1989. Our experience with IMA started with a single attached graft for proximal left anterior descending lesions in young patients affected from stable angina. After that our indications became more extensive. One IMA was utilized in 209 cases, both two IMAs in the remaining 9. Sequential IMA graft was performed in 16 patients and free IMA graft in 8. There were 242 IMA anastomosis and 295 associated vein by-passes. The overall operative mortality was 2.3%. Perioperative complications include myocardial infarction in 3 (1.4%), reoperation for bleeding in 4 (1.8%) and sternal wound complication in 4 (1.8%). These results are comparable to those of patients having only saphenous vein by-pass during the same period. At the follow-up actuarial survival rate at 42 months was 94 1.8% and 90% of these patients were completely asymptomatic. We include that IMA grafting shows low operative risk and provide excellent short term results. Our findings and the high long term patency rate of this conduit encourage us to extend the indication to IMA and to perform those surgical techniques that make possible multiple mammary coronary anastomosis.

摘要

本报告回顾了1986年至1989年间接受单纯内乳动脉(IMA)移植或联合静脉移植的218例患者。我们对IMA的应用始于为患有稳定型心绞痛的年轻患者的近端左前降支病变进行单支附着移植。此后,我们的适应证范围更广。209例患者使用了一支IMA,其余9例使用了两支IMA。16例患者进行了序贯IMA移植,8例进行了游离IMA移植。共进行了242次IMA吻合和295次相关静脉旁路手术。总体手术死亡率为2.3%。围手术期并发症包括3例(1.4%)心肌梗死、4例(1.8%)因出血再次手术和4例(1.8%)胸骨伤口并发症。这些结果与同期仅行大隐静脉旁路手术的患者相当。随访时,42个月的精算生存率为94±1.8%,其中90%的患者完全无症状。我们认为IMA移植手术风险低,短期效果良好。我们的研究结果以及该血管的高长期通畅率促使我们扩大IMA的适应证,并开展那些能够实现多次乳内动脉-冠状动脉吻合的手术技术。

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