Gropen T I, Gagliano P J, Blake C A, Sacco R L, Kwiatkowski T, Richmond N J, Leifer D, Libman R, Azhar S, Daley M B
Department of Neurology, Long Island College Hospital and State University of New York-Health Science Center at Brooklyn, 11201, USA.
Neurology. 2006 Jul 11;67(1):88-93. doi: 10.1212/01.wnl.0000223622.13641.6d.
Many hospitals lack the infrastructure required to treat patients with acute stroke. The Brain Attack Coalition (BAC) published guidelines for the establishment of primary stroke centers.
To determine if stroke center designation and selective triage of acute stroke patients improve quality of care.
Baseline chart abstraction was performed on all stroke patients admitted to 32 hospitals serving Brooklyn and Queens, NY, from March to May 2002. Hospitals were invited to meet BAC guideline-based criteria. Adherence was verified by on-site visits. After designation, acute stroke patients were selectively triaged. Remeasurement data were collected from August to October 2003.
The authors abstracted 1,598 charts at baseline and 1,442 charts at remeasurement. From baseline to remeasurement, median times decreased for door to physician contact (25 vs 15 minutes, p = 0.001), CT performance for potential tissue plasminogen activator (t-PA) candidates (68 vs 32 minutes, p < 0.001), and t-PA administration (109 vs 98 minutes (p = NS). IV t-PA utilization increased from 2.4 to 5.2% (p < 0.005), select t-PA protocol violations decreased from 11.1 to 7.9% (p = NS), and the stroke unit admission rate increased from 16 to 39% (p < 0.001). In stroke centers (n = 14) vs nondesignated hospitals (n = 18), there were shorter median times from door to physician contact (10 vs 25 minutes, p < 0.001), CT performance for potential t-PA candidates (31 vs 40 minutes, p = NS), and t-PA administration (95 vs 115 minutes, p < 0.05). Stroke centers, compared with nondesignated centers, admitted acute stroke patients to stroke units more often (55.9 vs 10.9%, p < 0.001).
Stroke center designation and selective triage of acute stroke patients improved the quality of care, including access to timely thrombolytic therapy and stroke units.
许多医院缺乏治疗急性中风患者所需的基础设施。脑卒中介入联盟(BAC)发布了建立初级卒中中心的指南。
确定卒中中心的指定和急性中风患者的选择性分诊是否能提高医疗质量。
对2002年3月至5月期间入住纽约布鲁克林和皇后区32家医院的所有中风患者进行基线病历摘要。邀请医院符合基于BAC指南的标准。通过现场访问核实依从情况。指定后,对急性中风患者进行选择性分诊。2003年8月至10月收集重新测量数据。
作者在基线时提取了1598份病历,重新测量时提取了1442份病历。从基线到重新测量,门到医生接触的中位时间减少(25分钟对15分钟,p = 0.001),潜在组织纤溶酶原激活剂(t-PA)候选者的CT检查时间(68分钟对32分钟,p < 0.001),以及t-PA给药时间(109分钟对98分钟,p = 无统计学意义)。静脉注射t-PA的使用率从2.4%提高到5.2%(p < 0.005),t-PA特定方案违规率从11.1%降至7.9%(p = 无统计学意义),卒中单元入住率从16%提高到39%(p < 0.001)。在卒中中心(n = 14)与未指定医院(n = 18)中,门到医生接触的中位时间更短(10分钟对25分钟,p < 0.001),潜在t-PA候选者的CT检查时间(31分钟对40分钟,p = 无统计学意义),以及t-PA给药时间(95分钟对115分钟,p < 0.05)。与未指定中心相比,卒中中心更常将急性中风患者收入卒中单元(55.9%对10.9%,p < 0.001)。
卒中中心的指定和急性中风患者的选择性分诊提高了医疗质量,包括及时获得溶栓治疗和卒中单元的机会。