Fuiano N, Procaccini D A, Pietrobelli A
Unità di Allergologia Pediatrica, A. USL Fg 1, San Severo, Foggia, Italy.
Minerva Pediatr. 2006 Jun;58(3):269-72.
The allergic rhinitis represents one of the ten major causes of ambulatory check-up. The incidence is between 10% to 25% in the general population and, in Italy, is approximately present in 10% of children and 20% of adolescents. The diagnosis of this disease is related to family anamnesis and the presence of several signs and typical symptoms. Regarding the tests used to detect this disease, cutaneous specific IgE (skin prick test) is used as cute reactivity expression. Using nasal specific IgE dosage we analyzed patients affected by rhinitis and its relationship between positive test, gender and age, the relationship between positive test and disease and the better response to diagnosis between the 2 tests performed (i.e., skin prick test and nasal specific IgE).
We analyzed 125 subjects enrolled consecutively, age range 48-216 months (median 144 months) that performed skin prick test and nasal specific IgE.
Looking at the overall subjects, 51 subjects were positive to skin prick test and nasal specific IgE, 23 subjects were positive to skin prick test, 31 subjects were positive to nasal specific IgE, 20 subjects were negative to both tests. Regarding the relationship between tests positive and symptoms we did not find any significant correlation.
Our data suggests that rhinitis diagnosis is quite difficult to perform and the test used to detect this disease needs to be more accurate and precise. Family anamnesis and clinical signs are fundamental in the diagnosis of allergic rhinitis.
过敏性鼻炎是门诊检查的十大主要病因之一。在普通人群中的发病率为10%至25%，在意大利，约10%的儿童和20%的青少年患有该病。该病的诊断与家族病史以及多种体征和典型症状有关。关于用于检测该病的检查，皮肤特异性IgE（皮肤点刺试验）用于表现即刻反应性。通过检测鼻特异性IgE，我们分析了鼻炎患者、阳性检测结果与性别和年龄之间的关系、阳性检测结果与疾病之间的关系以及两种检查（即皮肤点刺试验和鼻特异性IgE）中对诊断的更好反应。
我们分析了连续纳入的125名受试者，年龄范围为48至216个月（中位数为144个月），这些受试者进行了皮肤点刺试验和鼻特异性IgE检测。
在所有受试者中，51名受试者皮肤点刺试验和鼻特异性IgE均为阳性，23名受试者皮肤点刺试验阳性，31名受试者鼻特异性IgE阳性，20名受试者两项检查均为阴性。关于检测阳性与症状之间的关系，我们未发现任何显著相关性。
我们的数据表明，鼻炎的诊断相当困难，用于检测该病的检查需要更加准确和精确。家族病史和临床体征在过敏性鼻炎的诊断中至关重要。
