Buccoliero G, Lonero G, Rollo M A, Romanelli C, Loperfido P, Cristiano L, Chimienti A, Angelini P, Resta F
Department of Infectious Disease, S.S. Annunziata Hospital, ASL TA/1, Taranto, Italy.
Minerva Pediatr. 2006 Jun;58(3):273-7.
Usually measles is not severe, but serious complications can occur and thus hospitalization is needed. The aim of this study was to assess the reasons of hospitalizations of the persons affected by measles and the severity of disease as a result of measles infection.
During an outbreak from 2002 to 2003 in the province of Taranto, 73 hospitalized persons affected by measles were evaluated.
The age of the 73 hospitalized patients ranged between 1 and 42 years old (median age 14.5 years). An hospitalizations rate of 63% was reported in the first 4 months of 2003. Measles-related complications were observed in 35.6% of cases. In 14 cases (19%) we observed a pneumonia with a concomitant myocardititis and pancreatitis in 2 cases. Postmeasles encephalitis was diagnosed in 7 cases (9.5%). In 2 cases a concomitant myelitis occurred, with the presence of sequelae at the time of discharge but none permanent. Measles related appendicitis was observed in 5 males (6.8%) and appendectomy was performed in all cases. Data analysis showed that the patients with an age <15 years old had a higher risk of complications than patients with an age > or =15 years. None death was reported.
At present, measles and its related complications continue to be a serious illness even in industrialized countries, only a complete immunization vaccine strategy could permit measles' eradication.
通常麻疹病情并不严重,但可能会出现严重并发症,因此需要住院治疗。本研究的目的是评估麻疹患者住院的原因以及麻疹感染导致的疾病严重程度。
在2002年至2003年塔兰托省的一次疫情期间,对73名因麻疹住院的患者进行了评估。
73名住院患者的年龄在1岁至42岁之间(中位年龄14.5岁)。2003年的前4个月报告的住院率为63%。35.6%的病例观察到与麻疹相关的并发症。14例(19%)出现肺炎,2例同时伴有心肌炎和胰腺炎。7例(9.5%)诊断为麻疹后脑炎。2例同时发生脊髓炎,出院时有后遗症,但无永久性后遗症。5名男性(6.8%)观察到与麻疹相关的阑尾炎,所有病例均进行了阑尾切除术。数据分析表明,年龄<15岁的患者比年龄≥15岁的患者发生并发症的风险更高。未报告死亡病例。
目前,即使在工业化国家,麻疹及其相关并发症仍然是一种严重疾病,只有完整的免疫疫苗策略才能实现麻疹的根除。