Noël B, Bron C, Künzle N, De Heller M, Panizzon R G
Department of Dermatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
J Eur Acad Dermatol Venereol. 2006 Jul;20(6):707-10. doi: 10.1111/j.1468-3083.2006.01578.x.
Multiple nodules of the scrotum are uncommonly reported. Their origin is controversial. Treatment is always surgical but the best procedure is still to be determined.
Five new cases are reported with description of the histopathological findings and surgical procedure.
Nodules of the scrotum were more frequent in patients with dark skin suggesting an ethnic susceptibility. No other predisposing factors were noted. Screening for disturbances of phosphate or calcium balance was negative. The following histopathological findings were observed: non-calcified epidermoid cysts (3 patients), calcified epidermoid cysts (1 patient) and nodular calcifications without epithelial or glandular structures (1 patient). Subtotal excisions of the scrotum wall using tumescent anaesthesia were performed in all patients without any significant complications. Cosmetic results were excellent. No new lesions were observed during the 1-year follow-up period.
Most cases of multiple nodules of the scrotum are due to non-calcified epidermoid cysts. The term scrotal calcinosis is therefore probably abusively used by many authors. Some cases of nodular calcifications may be due to dystrophic calcification of epidermoid cysts, but calcifications may also occur without any visible epithelial or glandular structure. Subtotal excision of the scrotum wall is a safe and effective surgical procedure to treat multiple nodules of the scrotum. Cosmetic results are excellent and recurrences are rare.
阴囊多发结节的报道并不常见。其起源存在争议。治疗通常采用手术方式,但最佳手术方法仍有待确定。
报告5例新病例,并描述其组织病理学发现及手术过程。
阴囊结节在肤色较深的患者中更为常见,提示存在种族易感性。未发现其他诱发因素。磷酸盐或钙平衡紊乱筛查结果为阴性。观察到以下组织病理学发现:非钙化表皮样囊肿(3例患者)、钙化表皮样囊肿(1例患者)以及无上皮或腺体结构的结节状钙化(1例患者)。所有患者均采用肿胀麻醉进行阴囊壁次全切除术,未出现任何严重并发症。美容效果极佳。在1年的随访期内未观察到新的病变。
大多数阴囊多发结节病例是由非钙化表皮样囊肿引起的。因此,许多作者可能滥用了“阴囊钙质沉着症”这一术语。一些结节状钙化病例可能是表皮样囊肿的营养不良性钙化,但钙化也可能在没有任何可见上皮或腺体结构的情况下发生。阴囊壁次全切除术是治疗阴囊多发结节的一种安全有效的手术方法。美容效果极佳且复发罕见。