Kuyken Willem, Watkins Ed, Holden Emily, Cook William
Mood Disorders Centre, School of Psychology, University of Exeter, Exeter, UK.
J Affect Disord. 2006 Nov;96(1-2):39-47. doi: 10.1016/j.jad.2006.05.017. Epub 2006 Jul 11.
Identifying high-risk adolescents and understanding first onset of depression in adolescence are important steps in reducing depression morbidity. There is compelling evidence that the personality dimension neuroticism is a risk factor for depression, but the vulnerability mechanism is not yet understood. This study examined the association between a hypothesized psychological vulnerability factor (rumination) and depression in adolescents.
A behavioural high-risk design differentiated a sample of 326 adolescents (aged 14-18) as either at normal or high risk for depression (operationalized as scores on a measure of neuroticism).
Adolescents at risk for depression reported more rumination than adolescents not at risk. We hypothesized that the well established relationship between neuroticism and depression would be mediated by rumination in cross-sectional analyses, and our findings suggest that rumination partially mediated this relationship.
The findings tentatively suggest that neuroticism acts as a risk factor for adolescent onset depression through increased tendency towards brooding rumination (i.e. moody self-evaluative dwelling) in response to depressed mood. Prospective and experimental research examining this mechanism is required.
识别高危青少年并了解青少年期抑郁症的首次发作是降低抑郁症发病率的重要步骤。有确凿证据表明,人格维度神经质是抑郁症的一个风险因素,但其易感性机制尚不清楚。本研究探讨了一种假设的心理易感性因素(反刍思维)与青少年抑郁症之间的关联。
采用行为高危设计,将326名青少年(年龄在14至18岁之间)样本区分为抑郁症正常风险组或高风险组(以神经质测量得分来界定)。
抑郁症高风险青少年比非高风险青少年报告了更多的反刍思维。我们假设在横断面分析中,神经质与抑郁症之间已确立的关系将由反刍思维介导,我们的研究结果表明反刍思维部分介导了这种关系。
研究结果初步表明,神经质通过对抑郁情绪做出反应时增加的沉思反刍倾向(即情绪化的自我评估性沉思),成为青少年期抑郁症发作的一个风险因素。需要开展前瞻性和实验性研究来检验这一机制。