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子宫内膜样癌的组织病理学特征与绝经前女性患者肿瘤进展状态的相关性

Histopatological aspects of endometroid carcinoma in correlation to the state of tumoral progression in women patients during their premenopausal period.

作者信息

Morărescu Mihaela Doina, Simionescu Cristiana, Roşculescu I, Bălă Serenada, Cernea N, Pătru Emilia

机构信息

Batiştei Medical Center, Bucharest.

出版信息

Rom J Morphol Embryol. 2006;47(1):53-8.

PMID:16838058
Abstract

The performed study has comprised a number of 60 endometrial carcinomas, prevailed from women aged in the premenstrual period, in whose cases we have followed also the appreciation of the differentiating grading as well as the various aspects in neoplasies progression. The appreciation of the differentiating grading has allowed their placing as it follows: 39 cases of endometroid carcinoma well differentiated, seven cases of endometroid carcinoma mildly differentiated and five cases of endometroid carcinoma poorly differentiated. The correlation of the differentiating grading with the stage of tumoral progression has allowed the observation of the fact that while well invasive differentiated endometroid adenocarcinoma have been limited to the level of the uterine body, mildly and poorly differentiated invasive endometroid carcinoma besides profound myometrial invasion have associated cervical invasion and metastasis in structures situated at a real distance.

摘要

所进行的研究包括60例子宫内膜癌,主要来自处于绝经前期的女性,在这些病例中,我们还对分化分级以及肿瘤进展的各个方面进行了评估。分化分级的评估结果如下:39例高分化子宫内膜样癌,7例中分化子宫内膜样癌,5例低分化子宫内膜样癌。分化分级与肿瘤进展阶段的相关性使我们观察到,高侵袭性的高分化子宫内膜样腺癌局限于子宫体水平,而中分化和低分化侵袭性子宫内膜样癌除了有深度肌层浸润外,还伴有宫颈浸润以及远处结构转移。

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Histopatological aspects of endometroid carcinoma in correlation to the state of tumoral progression in women patients during their premenopausal period.子宫内膜样癌的组织病理学特征与绝经前女性患者肿瘤进展状态的相关性
Rom J Morphol Embryol. 2006;47(1):53-8.
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Tumor-associated macrophages correlate with vascular space invasion and myometrial invasion in endometrial carcinoma.肿瘤相关巨噬细胞与子宫内膜癌的血管间隙浸润及肌层浸润相关。
Gynecol Oncol. 2008 Apr;109(1):122-8. doi: 10.1016/j.ygyno.2007.12.033. Epub 2008 Mar 4.
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Endometrial endometrioid adenocarcinoma: a pathologic analysis of 827 consecutive cases.子宫内膜样腺癌:827例连续病例的病理分析
Am J Clin Pathol. 2008 Jan;129(1):110-4. doi: 10.1309/UDYANQ6XTK6UUTXQ.
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Problems in the differential diagnosis of endometrial hyperplasia and carcinoma.子宫内膜增生与癌的鉴别诊断问题
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Difficulties in assessing the depth of myometrial invasion in endometrial carcinoma.评估子宫内膜癌肌层浸润深度的困难。
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Adenomyosis involved by endometrial adenocarcinoma is a significant risk factor for deep myometrial invasion.子宫内膜腺癌累及子宫腺肌病是子宫肌层深部浸润的重要危险因素。
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Stage II endometrioid adenocarcinoma of the endometrium: clinical implications of cervical stromal invasion.子宫内膜样腺癌II期:宫颈间质浸润的临床意义。
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