麻醉大鼠结直肠扩张诱导的心率反射性抑制及心脏交感神经传出活动
Reflex inhibition of heart rate and efferent cardiac sympathetic outflow induced by colorectal distension in anesthetized rats.
作者信息
Li W M, Suzuki A
机构信息
Department of Integrative Medicine, Shanghai Medical College, Fudan University, Shanghai, China.
出版信息
J Physiol Sci. 2006 Apr;56(2):187-90. doi: 10.2170/physiolsci.SC003506. Epub 2006 May 9.
PMID:16839450
Abstract
Colorectal distensions of 60 and 80 mmHg significantly reduced heart rate (HR) and cardiac sympathetic nerve activity in anesthetized rats. This bradycardiac response was not influenced by the intravenous administration of atropine, but was abolished by propranolol, suggesting that it was elicited by sympathetic but not vagal efferent nerves.
摘要
60和80毫米汞柱的结肠扩张显著降低了麻醉大鼠的心率（HR）和心脏交感神经活动。这种心动过缓反应不受静脉注射阿托品的影响，但被普萘洛尔消除，表明它是由交感神经而非迷走神经传出神经引发的。
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