Dunn Kate M, Croft Peter R
Primary Care Musculoskeletal Research Centre, Primary Care Sciences, Keele University, Staffordshire, UK.
Pain. 2006 Dec 15;126(1-3):10-5. doi: 10.1016/j.pain.2006.06.005. Epub 2006 Jul 13.
Low back pain is considered to fluctuate over time, and related prognostic factors may behave similarly, therefore classification of prognosis may be affected by timing of assessment. We aimed to investigate the implications of timing of assessment of prognosis in low back pain. In a prospective cohort of primary care low back pain consulters aged 30-59 years, 359 returned questionnaires at baseline, one-month and one-year. The stability of selected prognostic indicators between baseline and one-month later was assessed, and relative risks for their association with outcome (individually and in combination) were calculated. Reported absence of most outcome indicators was stable between baseline and one-month. However, among people reporting presence of indicators at baseline, only around half still reported them a month later. There were no important differences between the prognostic strength of indicators measured at baseline or one-month. People reporting presence of indicators at either point had significantly higher risk of poor outcome than people not reporting the indicator at all. Presence of the indicators at both time points was associated with even higher risk; people with persistent high pain intensity had 15 times the risk of a poor outcome (relative risk 15.1; 95% confidence interval 6.7-33.8) compared with people not reporting high pain at either point. Combining information on prognostic indicators from two time points provides better classification of low back pain patients' eventual outcome than a single measurement alone. This increased accuracy in predicting prognosis is relevant to both clinical and research practice.
下腰痛被认为会随时间波动,相关的预后因素可能也有类似表现,因此预后分类可能会受到评估时间的影响。我们旨在研究下腰痛预后评估时间的影响。在一个年龄为30 - 59岁的基层医疗下腰痛咨询者的前瞻性队列中,359人在基线、1个月和1年时返回了问卷。评估了基线和1个月后选定预后指标的稳定性,并计算了它们与结局(单独及联合)关联的相对风险。报告的大多数结局指标在基线和1个月之间是稳定的。然而,在基线时报告有指标的人群中,1个月后仍报告有这些指标的只有大约一半。在基线或1个月时测量的指标的预后强度没有重要差异。在任何一个时间点报告有指标的人群比完全未报告该指标的人群预后不良的风险显著更高。两个时间点都有指标与更高的风险相关;与在两个时间点都未报告高疼痛强度的人群相比,持续高疼痛强度的人群预后不良的风险高15倍(相对风险15.1;95%置信区间6.7 - 33.8)。结合两个时间点的预后指标信息比单独一次测量能更好地对下腰痛患者的最终结局进行分类。这种在预测预后方面提高的准确性与临床和研究实践都相关。