Dunn Kate M, Croft Peter R, Main Chris J, Von Korff Michael
Primary Care Musculoskeletal Research Centre, Keele University, Staffordshire ST5 5BG, UK.
Pain. 2008 Mar;135(1-2):48-54. doi: 10.1016/j.pain.2007.05.001. Epub 2007 Jun 13.
A novel prognostic approach to defining chronic pain was developed in a US primary care low back pain population, using a combination of information about pain history, current status and likely prognosis. We tested whether this method was generalizable to a UK population. A prospective cohort of 426 patients who consulted with back pain at one of five UK general practices, and who returned follow-up information 1-year later were included. A baseline risk score was calculated based on pain severity and prognostic measures (depression, diffuse pain, pain duration), and cut-points from the US study applied for the risk of future clinically significant back pain, as defined by Chronic Pain Grades 2-4. New cut-points were also derived for the UK population using identical methods. The cut-points for probable and possible chronic pain developed in the US population (80% and 50% probability of future clinically significant back pain, respectively) were appropriate for the UK population, but the cut-point for classifying people at low risk (20% probability) was not replicated in the UK sample. The newly derived cut-points in the UK sample were similar; they remained the same for probable chronic pain, were slightly increased for possible chronic pain, and slightly reduced for those at intermediate or low risk. This method for defining chronic pain prospectively, using risk thresholds for future clinically significant pain, appears to be generalizable to a UK back pain population, particularly for identifying probable chronic pain, and may be generalizable to other primary care low back pain populations.
在美国初级保健腰痛人群中,开发了一种结合疼痛病史、当前状况和可能预后信息来定义慢性疼痛的新预后方法。我们测试了该方法是否适用于英国人群。纳入了一个前瞻性队列,其中426名在英国五家全科诊所之一因腰痛就诊且一年后返回随访信息的患者。根据疼痛严重程度和预后指标(抑郁、弥漫性疼痛、疼痛持续时间)计算基线风险评分,并应用美国研究中的切点来评估未来临床上显著腰痛的风险,如慢性疼痛分级2 - 4所定义。还使用相同方法为英国人群得出了新的切点。美国人群中确定的可能慢性疼痛和疑似慢性疼痛的切点(分别为未来临床上显著腰痛的概率80%和50%)适用于英国人群,但英国样本中未重现低风险人群(概率20%)的切点。英国样本中新得出的切点相似;可能慢性疼痛的切点保持不变,疑似慢性疼痛的切点略有增加,中等或低风险人群的切点略有降低。这种使用未来临床上显著疼痛的风险阈值来前瞻性定义慢性疼痛的方法似乎适用于英国腰痛人群,特别是用于识别可能的慢性疼痛,并且可能适用于其他初级保健腰痛人群。