Fang Xin, Wang Yuanyuan, Wang Weiqi
Department of Electronic Engineering, Fudan University, Shanghai 200433, China.
Ultrasonics. 2006 Dec 22;44 Suppl 1:e173-7. doi: 10.1016/j.ultras.2006.06.028. Epub 2006 Jun 30.
As a non-invasive method, the Doppler ultrasound technique is used to detect the vessel stenosis. To search for characteristics of Doppler ultrasound signals sensitive to the stenosis, a computer simulation approach is proposed in this paper to generate Doppler ultrasound signals from vessels with various stenosis degrees. The blood flow velocity distribution in a stenosed vessel is firstly calculated using the transient finite element method (FEM). Then the power spectral density of Doppler signals is estimated using the overall-distribution nonparametric estimation method. Finally Doppler signals are generated using the cosine-superposed method. The proposed approach is proved to be useful for simulating Doppler ultrasound signals from vessels with various stenosis degrees. It is also shown that characteristics of Doppler ultrasound signals may be used to estimate the vessel's stenosis degree.
作为一种非侵入性方法,多普勒超声技术用于检测血管狭窄。为了寻找对狭窄敏感的多普勒超声信号特征,本文提出一种计算机模拟方法,用于生成来自不同狭窄程度血管的多普勒超声信号。首先使用瞬态有限元法(FEM)计算狭窄血管中的血流速度分布。然后使用全分布非参数估计方法估计多普勒信号的功率谱密度。最后使用余弦叠加法生成多普勒信号。所提出的方法被证明对于模拟来自不同狭窄程度血管的多普勒超声信号是有用的。还表明,多普勒超声信号的特征可用于估计血管的狭窄程度。