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一例天然除臭剂引起的变应性接触性皮炎:4例与地衣酸混合物过敏相关的报告

Allergic contact dermatitis from a natural deodorant: a report of 4 cases associated with lichen acid mix allergy.

作者信息

Sheu Mary, Simpson Eric L, Law Sandra V, Storrs Frances J

机构信息

Oregon Health and Sciences University, Portland, OR 97201, USA.

出版信息

J Am Acad Dermatol. 2006 Aug;55(2):332-7. doi: 10.1016/j.jaad.2004.12.043.

Abstract

BACKGROUND

Botanical ingredients used in personal care products are a significant and underreported cause of allergic contact dermatitis.

OBJECTIVE

To evaluate allergic contact dermatitis from a widely-used botanical deodorant.

METHODS

We conducted patch testing in four patients who were using the botanical deodorant and were referred to the contact dermatitis clinic; three patients had axillary dermatitis and one had dermatitis of the external ear.

RESULTS

All four patients had positive patch test reactions to lichen acid mix and D-usnic acid. Of the three patients who were patch tested to the botanical deodorant, all had positive reactions.

LIMITATIONS

We did not test to the specific lichen used in the natural deodorant but rather used our own lichen acid mix and d-usnic acid in addition to testing to the actual product. One of the patients declined to be tested with the natural deodorant, but did test positive to the lichen acid mix and d-usnic acid.

CONCLUSION

Personal care products such as deodorants may represent a new route of exposure to lichen extract, a known allergen.

摘要

背景

个人护理产品中使用的植物成分是变应性接触性皮炎的一个重要但未被充分报道的原因。

目的

评估一种广泛使用的植物除臭剂引起的变应性接触性皮炎。

方法

我们对四名使用该植物除臭剂并被转诊至接触性皮炎诊所的患者进行了斑贴试验;三名患者患有腋窝皮炎,一名患有外耳皮炎。

结果

所有四名患者对地衣酸混合物和D-松萝酸的斑贴试验反应均为阳性。在对该植物除臭剂进行斑贴试验的三名患者中,所有人的反应均为阳性。

局限性

我们没有对天然除臭剂中使用的特定地衣进行检测,而是除了对实际产品进行检测外,还使用了我们自己的地衣酸混合物和D-松萝酸。其中一名患者拒绝用天然除臭剂进行检测,但对地衣酸混合物和D-松萝酸的检测呈阳性。

结论

除臭剂等个人护理产品可能是接触已知过敏原地衣提取物的一条新途径。

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