D'Amato Alberto, Pezzoli Francesca, Balducci Genoveffa, Bocchetti Tommaso, Ziparo Vincenzo
UOC Chirurgia Generale A - Azienda Ospedaliera Sant'Andrea - II Facoltà di Medicina e Chirurgia Università degli Studi di Roma La Sapienza - Roma.
Chir Ital. 2006 May-Jun;58(3):377-81.
We describe a case of gastric metastases from a lobular carcinoma of the breast in a 73-year-old woman who had undergone a left mastectomy with axillary dissection 15 years earlier. The initial diagnosis was diffuse-type gastric carcinoma as evaluated both by analysis of gastric biopsy findings and ultrasonographic endoscopy. The definitive diagnosis of metastatic breast cancer was confirmed after subtotal gastrectomy for a presumed primary gastric carcinoma and was obtained using a panel of specific immunohistochemical markers. The distinction between primary and secondary gastric malignancies in patients with a history of lobular breast carcinoma may not be merely an academy exercise, since the treatment and prognosis of the two situations are different.
我们描述了一例73岁女性胃转移性小叶乳腺癌病例，该患者15年前接受了左侧乳房切除术及腋窝淋巴结清扫术。通过对胃活检结果分析及超声内镜检查，最初诊断为弥漫型胃癌。在因疑似原发性胃癌行胃次全切除术后，经一组特异性免疫组化标志物确诊为转移性乳腺癌。对于有小叶乳腺癌病史的患者，区分原发性和继发性胃恶性肿瘤不仅仅是学术探讨，因为这两种情况的治疗和预后不同。
